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Neurogenic orthostatic hypotension after treatment with sorafenib [PDF]
A man in his 70s with a history of fatigue, abdominal pain, and a palpable abdominal mass was found to have a peritoneal desmoid tumour. One year after diagnosis, he was prescribed sorafenib to limit tumour growth. Two months later, he developed dyspnoea on exertion and lower extremity weakness and was reported to have supine hypertension and ...
Catherine, Wegner Wippel+3 more
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Norepinephrine reuptake blockade to treat neurogenic orthostatic hypotension [PDF]
<jats:title>Abstract</jats:title><jats:p>GNSS satellite and receiving antennas exhibit group delay variations (GDV), which affect code pseudorange measurements. Like antenna phase center variations, which affect phase measurements, they are frequency-dependent and vary with the direction of the transmitted and received signal.
Eisenhofer, Graeme, Goldstein, David S.
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Neurogenic Orthostatic Hypotension. Lessons From Synucleinopathies [PDF]
Abstract Maintenance of upright blood pressure critically depends on the autonomic nervous system and its failure leads to neurogenic orthostatic hypotension (NOH). The most severe cases are seen in neurodegenerative disorders caused by abnormal α-synuclein deposits: multiple system atrophy (MSA), Parkinson’s disease, Lewy body dementia,
Juan Francisco Idiaquez+3 more
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Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer [PDF]
Parkinson disease (PD) is associated with a variety of motor and non-motor clinical manifestations, including cardiovascular autonomic dysfunction. Neurogenic orthostatic hypotension (nOH) is a potentially serious manifestation of cardiovascular sympathetic failure that occurs in approximately 30% of patients with PD. Here we review the pathophysiology
Phillip A. Low+1 more
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Neurogenic Orthostatic Hypotension: State of the Art and Therapeutic Strategies [PDF]
Neurogenic orthostatic hypotension (nOH) is a subtype of orthostatic hypotension in which patients have impaired regulation of standing blood pressure due to autonomic dysfunction. Several primary and secondary causes of this disease exist. Patients may present with an array of symptoms making diagnosis difficult.
Dinesh K Kalra, Anvi Raina, Sumit Sohal
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Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension [PDF]
AbstractObjectiveThe efficacy and safety of 1‐month atomoxetine and midodrine therapies were compared. Three‐month atomoxetine and combination therapies were investigated for additional benefits.MethodsThis prospective open‐label randomized trial included 50 patients with symptomatic neurogenic orthostatic hypotension (nOH).
Woo Jin Lee+25 more
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Six‐Month Use of Droxidopa for Neurogenic Orthostatic Hypotension [PDF]
ABSTRACTBackgroundDroxidopa is approved for adult patients with symptomatic neurogenic orthostatic hypotension (nOH); there is limited information regarding effects on symptoms, outcomes, and quality of life (QOL) beyond two weeks of treatment.ObjectiveExamine the real‐world experience of patients taking droxidopa after six months of treatment ...
Kim McLeod+11 more
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Neurogenic orthostatic hypotension: the very basics [PDF]
Horacio Kaufmann, Jose-Alberto Palma
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A validated test for neurogenic orthostatic hypotension at the bedside [PDF]
Horacio Kaufmann+2 more
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Primary neurogenic orthostatic hypotension [PDF]
Eight further cases of neurogenic orthostatic hypotension are described together with a necropsy study on one case. Three cases showed evidence of autonomic dysfunction in isolation, while in five cases this was accompanied by evidence of more diffuse central nervous system degeneration.
N. E. F. Cartlidge+2 more
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