Results 1 to 10 of about 985,944 (229)
Psoralen Photochemistry and Nucleic Acid Structure
Journal of Investigative Dermatology, 1981 Many new psoralen derivatives have been synthesized in an effort to enhance their water solubility and their binding to nucleic acids. Availability of the very soluble strongly binding compounds has improved our abilities to follow the optical changes associated with the photochemistry of psoralens with DNA.
J. Hearst
semanticscholar +5 more sources
Chemical etiology of nucleic acid structure [PDF]
Pure and Applied Chemistry, 2000 Abstract The synthesis of potentially natural nucleic acid alternatives and comparison of some of their chemical properties with those of RNA and DNA have led to findings that we consider to be relevant in the context of a chemical etiology of nucleic acid structure.
Eschenmoser, A., Krishnamurthy, R.
semanticscholar +9 more sources
Linking molecular models with ion mobility experiments. Illustration with a rigid nucleic acid structure. [PDF]
J Mass Spectrom, 2015 Ion mobility spectrometry experiments allow the mass spectrometrist to determine an ion's rotationally averaged collision cross section ΩEXP. Molecular modelling is used to visualize what ion three-dimensional structure(s) is(are) compatible with the ...
D'Atri V, Porrini M, Rosu F, Gabelica V.
europepmc +2 more sources
THE CLASSIC: Molecular Structure of Nucleic Acids [PDF]
Clinical Orthopaedics & Related Research, 1953 WE wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological interest. A structure for nucleic acid has already been proposed by Pauling and Corey1. They kindly made their manuscript available to us in advance of publication.
James D. Watson, Francis Crick
openaire +11 more sources
Structural Probes in Quadruplex Nucleic Acid Structure Determination by NMR [PDF]
Molecules, 2012 Traditionally, isotope-labelled DNA and RNA have been fundamental to nucleic acid structural studies by NMR. Four-stranded nucleic acid architectures studies increasingly benefit from a plethora of nucleotide conjugates for resonance assignments, the ...
Mateus Webba da Silva +1 more
doaj +2 more sources
CHEMICAL STRUCTURE OF THE NUCLEIC ACIDS [PDF]
Proceedings of the National Academy of Sciences, 1954 A. R. Todd
openaire +5 more sources
Pre-existing Distortions in Nucleic Acid Structure Aid Polypurine Tract Selection by HIV-1 Reverse Transcriptase* [PDF]
Journal of Biological Chemistry, 2002 Precise cleavage at the polypurine tract (PPT)/U3 junction by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase RNase H is critical for generating a correct viral DNA end for subsequent integration.
M. Kvaratskhelia +2 more
semanticscholar +2 more sources
Impact of Liposomal Spherical Nucleic Acid Structure on Immunotherapeutic Function [PDF]
ACS Central Science, 2021 Cassandra E. Callmann +4 more
doaj +2 more sources
A structure for deoxyribose nucleic acid
Journal of the American College of Cardiology, 2003 This past April marked the 50th anniversary of publication of the manuscript describing the double helix structure of deoxyribonucleic acid (DNA) by James Watson and Francis Crick [(1)][1]. This was, of course, truly a landmark publication and has been said to have given birth to the field ...
Anthony N. DeMaria
openaire +3 more sources
Development of novel nucleic acid therapy aimed at directly controlling liver fibrosis [PDF]
Molecular Therapy: Nucleic AcidsCurrently, no drugs directly treat liver fibrosis. Previously, we have shown that treatment with miR-29a-3p improved liver fibrosis in a mouse model. To investigate the effectiveness of nucleic acid therapy at a lower dose, a modified nucleic acid was ...
Tomohiro Umezu +7 more
doaj +2 more sources