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In 2005, Kosfeld et al. published their now seminal paper showing that intranasal oxytocin (OXT) administration increased interpersonal trust (Kosfeld et al., 2005). This finding spawned broad interest into the effects of OXT on social and emotional behavior in humans (Bos et al., 2012), and its implications for translational medicine (Meyer-Lindenberg
Richard A.I. Bethlehem+8 more
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The mammalian host microbiome affects many targets throughout the body, at least in part through an integrated gut-brain-immune axis and neuropeptide hormone oxytocin. It was discovered in animal models that microbial symbionts, such as Lactobacillus reuteri, leverage perinatal niches to promote multigenerational good health and reproductive fitness ...
Bernard J. Varian+2 more
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Abstract N-Carbobenzoxy-S-methoxybenzyl-l-cysteinyl-l-tyrosyl-l-isoleucyl-l-glutaminyl-l-asparagin-yl-S-p-methoxybenzyl-l-cysteinyl-l-prolyl-l-leucylglycinamide (IX) was synthesized by the step-wise elongation method, and highly potent oxytocin was obtained from IX by treatment not only with sodium in liquid ammonia, but also with ...
Shumpei Sakakibara+3 more
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A Highly Potent Analogue of Oxytocin, Desamino-oxytocin
Derek B. Hope+2 more
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Characterization and Expression of Oxytocin and the Oxytocin Receptor
Oxytocin, a nonapeptide hormone and neurotransmitter, is expressed in a variety of tissues, as are its receptors. In vivo, oxytocin acts as a paracrine and/or autocrine mediator of multiple biological effects. These effects are exerted primarily through interactions with G-protein-coupled oxytocin/vasopressin receptors, which, via G(q) and G(i ...
Yuji Kaneko, Hideki Shojo
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Kuramoto model based analysis reveals oxytocin effects on brain network dynamics [PDF]
The oxytocin effects on large-scale brain networks such as Default Mode Network (DMN) and Frontoparietal Network (FPN) have been largely studied using fMRI data. However, these studies are mainly based on the statistical correlation or Bayesian causality inference, lacking interpretability at physical and neuroscience level.
arxiv
One of the most meaningful results recently achieved in bone research has been to reveal that the pituitary hormones have profound effect on bone, so that the pituitary-bone axis has become one of the major topics in skeletal physiology. Here, we discuss the relevant evidence about the posterior pituitary hormone oxytocin (OT), previously thought to ...
Graziana Colaianni+3 more
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SERS discrimination of single amino acid residue in single peptide by plasmonic nanocavities [PDF]
Surface-enhanced Raman spectroscopy (SERS) is a sensitive label-free optical method that can provide fingerprint Raman spectra of biomolecules such as DNA, amino acids and proteins. While SERS of single DNA molecule has been recently demonstrated, Raman analysis of single protein sequence was not possible because the SERS spectra of proteins are ...
arxiv +1 more source