Results 1 to 10 of about 76,980 (312)
Thiol Peroxidases as Major Regulators of Intracellular Levels of Peroxynitrite in Live Saccharomyces cerevisiae Cells [PDF]
Antioxidants, 2020 Thiol peroxidases (TP) are ubiquitous and abundant antioxidant proteins of the peroxiredoxin and glutathione peroxidase families that can catalytically and rapidly reduce biologically relevant peroxides, such as hydrogen peroxide and peroxynitrite ...
André Luís Condeles +4 more
doaj +2 more sources
Role of Peroxynitrite in the Pathogenesis of Parkinson’s Disease and Its Fluorescence Imaging-Based Detection [PDF]
BiosensorsParkinson’s disease (PD) is the second most common neurodegenerative disorder, affecting the lives of millions of people worldwide. Although the mechanism underlying PD pathogenesis is largely undefined, increasing evidence indicates that oxidative and ...
Jiye Lv +5 more
doaj +2 more sources
Homogenous catalysis of peroxynitrite conversion to nitrate by diaryl selenide: a theoretical investigation of the reaction mechanism [PDF]
Frontiers in ChemistryQuenching peroxynitrite (a reactive oxidant species) is a vital process in biological systems and environmental chemistry as it maintains redox balance and mitigates damaging effects in living cells and the environment.
Yuan Xue +5 more
doaj +2 more sources
Sonochemical formation of peroxynitrite in water: Impact of ultrasonic frequency and power
Ultrasonics Sonochemistry, 2023 There is a lack of literature on peroxynitrite formation due to sonolysis of aerated water. In this work, the impact of sonication parameters, frequency and power, on ultrasonic peroxynitrite production in aerated alkaline water was investigated ...
Hamza Ferkous +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2022 Glutathione peroxidase 1 (GPX1) is a crucial antioxidant enzyme that prevented the harmful accumulation of intra-cellular hydrogen peroxide. GPX1 might contribute in limiting cochlear damages associated with aging or acoustic overexposure, but the ...
Xue Wang +15 more
doaj +1 more source
Redox Biology, 2022 The diffusion-limited reaction of nitric oxide (NO) and superoxide (O2−) produces peroxynitrite (ONOO−), a biological oxidant that has been implicated in a number of pathological conditions, including neurodegenerative disorders.
Megan Jandy +17 more
doaj +1 more source
The protective role of Wnt3a in peroxynitrite-induced damage of cochlear hair cells in vitro
Brazilian Journal of Otorhinolaryngology, 2023 Objective: To investigate the effect of peroxynitrite on the cultured cochlear hair cells of C57BL/6 P3 mice in vitro as well as the role of Wnt3a, as an activator of the canonical Wnt signaling pathway, underlying the action of such an oxidative stress.
Fengyun Cui +3 more
doaj +1 more source
FeTPPS, a Peroxynitrite Decomposition Catalyst, Ameliorates Nitrosative Stress in Human Spermatozoa
Antioxidants, 2023 Excessive levels of reactive nitrogen species (RNS), such as peroxynitrite, promote nitrosative stress, which is an important cause of impaired sperm function.
Pamela Uribe +9 more
doaj +1 more source
The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite
Biomolecules, 2021 While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H2DCF, so we concluded that
André Luís Condeles +1 more
doaj +1 more source
Antioxidants, 2022 Nitrobindins (Nbs) are all-β-barrel heme proteins and are present in prokaryotes and eukaryotes. Although their function(s) is still obscure, Nbs trap NO and inactivate peroxynitrite.
Giovanna De Simone +4 more
doaj +1 more source