Results 1 to 10 of about 119,934 (290)

Evidences for gestures associated with pruritus in very young infants: a pilot study [PDF]

Scientific Reports
The anatomical and functional basis for pruritus is present from birth. However, pruritus in this population is largely underestimated. The aim of this study was to analyze behaviors potentially associated with pruritus in infants under 6 months ...
Adrien Boyard, Camille Cosnard, David Simon, Camille Le Pors, Claire Abasq-Thomas, Marine Grandgeorge, Laurent Misery, Séverine Henry, Jean-Michel Roué   +8 more
doaj   +2 more sources

Scratching increases epidermal neuronal branching and alters psychophysical testing responses in atopic dermatitis and brachioradial pruritus

Frontiers in Molecular Neuroscience, 2023
BackgroundChronic scratching imposes a major stress on the skin and can lead to itch intensity worsening, and consequently, patients may enter an itch–scratch cycle.
Lina Renkhold, Henning Wiegmann, Bettina Pfleiderer, Aysenur Süer, Claudia Zeidler, Manuel P. Pereira, Manuel P. Pereira, Martin Schmelz, Sonja Ständer, Konstantin Agelopoulos   +9 more
doaj   +1 more source

Association between pruritus and serum concentrations of parathormone, calcium and phosphorus in hemodialysis patients. [PDF]

, 2013
Chronic renal disorders have a progressive course in most cases, and finally result in end-stage renal disease (ESRD). Hemodialysis (HD) is one of the mainstays in the treatment of these patients. Disturbance in calcium (Ca) and phosphorus (P) metabolism
Bayzayi, F., Haddad, M., Joshaghani, H.R., Qorbani, M., Tajbakhsh, R.   +4 more
core   +5 more sources

Hand Pruritus: Clinical Profile, Functional Impairment and Disease-related Burden in a Prospective Cohort Study of 395 Patients

Acta Dermato-Venereologica, 2021
Human hands are complex structures essential for a variety of functions in everyday life. This study prospectively investigated the clinical features of hand pruritus and the resulting functional impairment and disease-related burden in 395 patients with
Teresa Gabriele Nau, Viola Rau, Claudia Zeidler, Sonja Ständer, Manuel P. Pereira   +4 more
doaj   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco, Francis, Heather, Kennedy, Lindsey, Kundu, Debjyoti, Meadows, Vik   +4 more
core   +1 more source

The Neuromodulatory Effect of Antipruritic Treatment of Chronic Prurigo

Dermatology and Therapy, 2019
Chronic prurigo is an extremely severe pruritic skin disease which presents with multiple, hyperkeratotic and erosive papules, nodules and/or plaques.
Claudia Zeidler, Manuel Pereira, Sonja Ständer   +2 more
doaj   +1 more source

Itch in Scabies—What Do We Know?

Frontiers in Medicine, 2021
Scabies is a common parasitic skin infestation characterized by severe itch and a heterogenous clinical presentation. Itch, as the cardinal symptom of scabies, is imposing a high burden on affected patients and is often difficult to manage.
Sascha Ständer, Sonja Ständer
doaj   +1 more source

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]

, 2019
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George, Bacon, Bruce, Bowlus, Christopher L, Dorenbaum, Alejandro, Gu, Joan, Hirschfield, Gideon M, Jones, David, Kennedy, Ciara, Levy, Cynthia, Luketic, Velimir, Mayo, Marlyn J, Medendorp, Sharon, Novak, Patricia, Patanwala, Imran, Pockros, Paul J, Vuppalanchi, Raj   +15 more
core   +2 more sources

Analysis of 325 Patients with Chronic Nodular Prurigo: Clinics, Burden of Disease and Course of Treatment

Acta Dermato-Venereologica, 2020
Chronic nodular prurigo presents with multiple pruriginous nodules and severe pruritus. This study aims to explore the treatment course and regimens in patients with chronic nodular prurigo and to analyse predictive factors contributing to therapeutic ...
Sonja Gründel, Manuel P. Pereira, Michael Storck, Nani Osada, Gudrun Schneider, Sonja Ständer, Claudia Zeidler   +6 more
doaj   +1 more source

Pruritus in Autoimmune and Inflammatory Dermatoses

Frontiers in Immunology, 2019
Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease ...
Claudia Zeidler, Manuel Pedro Pereira, Flavien Huet, Flavien Huet, Laurent Misery, Laurent Misery, Kerstin Steinbrink, Sonja Ständer   +7 more
doaj   +1 more source