Results 171 to 180 of about 289,950 (199)

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Development and validation of a novel triplex droplet digital PCR assay for simultaneous detection of African swine fever virus, pseudorabies virus, and porcine parvovirus. [PDF]

Front Microbiol
Yu J, Zhu L, Zuo Y, Gao S, Wang Q, Xu J, Fang L, Liu Y, Liu S, Wang X, Wang X, Wang Y, Li J, Bao J, Wang Z.   +14 more
europepmc   +1 more source

Near‐Infrared Cocrystal Nanofluorophore with Enhanced Two‐Photon Absorption Cross Sections

Advanced Science, EarlyView.
In this study, organic cocrystal nanoparticles (BP4TC‐NPs) were prepared via a nanoprecipitation method using an amphiphilic surfactant. The resulting cocrystal nanoparticles exhibit exceptional nonlinear optical properties and bioimaging capabilities.
Liangmeng Hao, Ying Ni, Jiawei Huang, Yucheng Wang, Fan Liu, Xu Wang, Lei Kang, Zheshuai Lin, Weigang Zhu   +8 more
wiley   +1 more source

The Use of CSF Multiplex PCR Panel in Patients with Viral Uveitis. [PDF]

Diagnostics (Basel)
Jeong YH, Park SH, Lee SM, Byon I, Yi J, Park SW.   +5 more
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Systematic evaluation and optimization of TaqMan qPCR assays targeting F<i>57</i>, ISMAP<i>02</i>, and IS<i>900</i> for multiplex detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>. [PDF]

J Clin Microbiol
Bissonnette N, Ollier S, Brousseau J-P, Byrne AS, Savard C, Tahlan K.   +5 more
europepmc   +1 more source

Caregiving In Multiplex Families With Severe Mental Illness: A Scoping Review Of Psychosocial Impacts And Evidence Gaps

R, Shama Shareen
openalex   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Surveillance of Acute Respiratory Infections in Central India (2024-2025) Using Multiplex RT-PCR. [PDF]

Infect Dis Clin Microbiol
Maity H, Deotale V, Attal R, S M.
europepmc   +1 more source

Engineering Favorable Propagation: Near-Field IRS Deployment for Spatial Multiplexing

Yuxuan Chen, Qingqing Wu, Guangji Chen, Qiaoyan Peng, Wen Chen   +4 more
openalex   +1 more source