Results 31 to 40 of about 472,101 (242)

Avalanche Collapse of Interdependent Network [PDF]

, 2012
We reveal the nature of the avalanche collapse of the giant viable component in multiplex networks under perturbations such as random damage. Specifically, we identify latent critical clusters associated with the avalanches of random damage.
A. V. Goltsev, D. Stauffer, G. J. Baxter, J. F. F. Mendes, S. N. Dorogovtsev   +4 more
core   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Strangles: The Molecular Identification and Epidemiology of Streptococcus equi subsp. equi [PDF]

, 2012
A conventional PCR diagnostic test was established to confirm the microbiological isolation of Streptococcus equi subsp. equi (S. equi), the causative agent of strangles.
Patty, Olivia Anne
core   +1 more source

Emergence of overlap in ensembles of spatial multiplexes and statistical mechanics of spatial interacting networks ensembles

, 2014
Spatial networks range from the brain networks, to transportation networks and infrastructures. Recently interacting and multiplex networks are attracting great attention because their dynamics and robustness cannot be understood without treating at the ...
Bianconi, Ginestra, Halu, Arda, Mukherjee, Satyam   +2 more
core   +1 more source

Finite connected components in infinite directed and multiplex networks with arbitrary degree distributions [PDF]

, 2017
This work presents exact expressions for size distributions of weak/multilayer connected components in two generalisations of the configuration model: networks with directed edges and multiplex networks with arbitrary number of layers.
Kryven, I.
core   +2 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Synchronization in Delayed Multiplex Networks

, 2015
We study impact of multiplexing on the global phase synchronizability of different layers in the delayed coupled multiplex networks. We find that at strong couplings, the multiplexing induces the global synchronization in sparse networks.
Ghosh, Saptarshi, Jalan, Sarika, Kurths, Jürgen, Singh, Aradhana   +3 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Topological enslavement in evolutionary games on correlated multiplex networks

, 2018
Governments and enterprises strongly rely on incentives to generate favorable outcomes from social and strategic interactions between individuals. The incentives are usually modeled by payoffs in evolutionary games, such as the prisoner's dilemma or the ...
Axelrod R M, Battiston F, Dirk Helbing, Grujić J, Kaj-Kolja Kleineberg, Newman M, Nowak M A, Nowak R H M, Smith J M, Szolnoki A, Szolnoki A, Wang Z, Wang Z   +12 more
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source