Results 181 to 190 of about 10,721,966 (298)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Injection Systems of Commercial Vehicles

This thesis summarizes information about injection systems used in commercial vehicles. Includes an overview of different types of injection systems, their differences in structure, function description and their pros and cons. The following is a list of
Cajzl, Štěpán
core  

Genome-wide Identification and Characterization of a Superfamily of Bacterial Extracellular Contractile Injection Systems.

Cell Rep, 2019
Chen L, Song N, Liu B, Zhang N, Alikhan NF, Zhou Z, Zhou Y, Zhou S, Zheng D, Chen M, Hapeshi A, Healey J, Waterfield NR, Yang J, Yang G.   +14 more
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Toward Long-Acting Injectable Antidepressants: Drug-Delivery Strategies, Clinical Considerations, and Regulatory Barriers. [PDF]

Pharmaceutics
Koppisetti H, Rajapaksha W, Nijhawan HP, Song Y, Youssef S, Garg S.   +5 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Nanoparticle delivery systems for gene therapy of degenerative musculoskeletal diseases. [PDF]

J Orthop Translat
Chen X, Sun J, Xie W, Arthur Vithran DT, Zhang Q, Rosenholm JM, Li Y, Zhang H, Huang C.   +8 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Experimental Study on the Mechanism and Effect of Middle-Phase Microemulsion Flooding in a Conglomerate Reservoir. [PDF]

ACS Omega
Shao H, Liu T, Guan D, Sun J, Tang W, Zhao Z, Luan H, Maimaiti P, Zhan J, Ren B.   +9 more
europepmc   +1 more source