Results 121 to 130 of about 468,604 (313)

SPEECH LEVEL PATTERN AND REFERENCE/ DEIXIS BASED ON SOCIAL STATUS CLASSIFICATION OF JAVANESE LANGUAGE USING (A STUDY ABOUT TRADITION AS INFLUENCE IN ISLAMIC ANCIENT BOARDING SCHOOL/PONDOK PESANTREN SALAFI LANGUAGE STYLE) [PDF]

open access: yes, 2012
Language in human’s using as the study has generally two scope of study; macrolinguistics,microlinguistics. Macrolinguistics as the study of language that occurs problematics of language relate to cognitive development, social interaction, and function ...
Sari , Kharisma Puspita
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Labour markets in a Post-Keynesian growth model: the effects of endogenous productivity growth and working time reduction [PDF]

open access: yes, 2020
We study endogenous employment and distribution dynamics in a Post-Keynesian model of Kalecki-Steindl tradition. Productivity adjustments stabilize employment and the labour share in the long run: technological change allows firms to replenish the ...
Ederer, Stefan, Rezai, Armon
core  

The defense function of the state: Traditional and modern understanding

open access: yesSrpska politička misao
To understand a phenomenon means to grasp its essence, that is, all the characteristics that define it and distinguish it from other phenomena. Since the defense function of the state is a complex phenomenon encompassing biological, anthropological, philosophical, sociological, psychological, political, security, military, strategic, and other aspects,
Milinko Vračar, Igor Barišić
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The Concept of an Agricultural Surplus, from Petty to Smith [PDF]

open access: yes
Everyone has to eat, so those who produce food must produce enough to feed themselves and to feed all those who do not produce their own food. Once stated.
Anthony Brewer
core  

Hybridizing old downtown Suwon City: how new urban fabric may save the past [PDF]

open access: yes, 2011
In response to paradigm shifts of environmental, social and economic methods at the local and global scales, new approaches are required for creating alternative urban models which emphasize sustainability and landscape productivity.
Lee, CheongJong
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy