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PLACENTAL TRANSFER OF NALOXONE [PDF]

open access: yesBritish Journal of Anaesthesia, 1986
Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m.
B.M. Hibbard, D. Davies, M. Rosen
openaire   +4 more sources

Naloxone Audit

open access: yesBJPsych Open, 2023
AimsThe aim of this audit was to look into the services’ fidelity of Naloxone provision and training across the Essex wide area compared with local guidelines as well as national guidelines (UK guidelines on clinical management of drug misuse and dependence, 2017)MethodsThe electronic records database for substance misuse services (THESEUS) was used ...
openaire   +1 more source

Population and species neighbor identity impact trait–trait relationships and plant performance

open access: yesPopulation Ecology, EarlyView.
We evaluated how populations and species identity influence plant performance and trait outcomes in mixtures, and assessed trait variation among populations of two forb species native to the western United States (Dieteria canescens and Heterotheca villosa) following three interaction treatments (single‐population monoculture, two‐population mixture ...
Alicia J. Foxx   +2 more
wiley   +1 more source

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

open access: yesPopulation Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji   +9 more
wiley   +1 more source

Combining transient dynamics and logistic‐asymptotic growth to study the recovery of two seabird populations after rat eradication

open access: yesPopulation Ecology, EarlyView.
This study examines the demographic dynamics of two seabird populations on Tromelin Island, 15 years after the eradication of brown rats. The results indicate that these populations are in good health and are expected to continue growing until breeding sites are saturated in about a century.
Merlène Saunier   +6 more
wiley   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

open access: yesPopulation Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Network topology drives population temporal variability in experimental habitat networks

open access: yesPopulation Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu   +3 more
wiley   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

open access: yesFEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta   +3 more
wiley   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

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