Results 41 to 50 of about 166,081,157 (256)
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Evaluation of the ICT Test Bed project: final report, June 2007 [PDF]
, 2007 The report describes three strands of evaluation used in the review of the 2006 outcomes from ICT Test Bed and the findings from each strand. a) Quantitative data: Benchmarking of changes in performance on national tests against matched comparator ...
Convery, Andy +11 more
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FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source
Emerging patterns of leadership: co-location, continuity and community [PDF]
, 2010 "Local leaders have taken hold of the opportunity created by co-location not just to deal with an immediate problem, but also to transcend that with an even better offer to children and their families." - Page ...
Allen, Tracey +3 more
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Meridional heat transport across the Antarctic Circumpolar Current by the Antarctic Bottom Water overturning cell [PDF]
, 2007 The heat transported by the lower limb of the Southern Ocean meridional overturning circulation is commonly held to be negligible in comparison with that transported by eddies higher in the water column.
Coward +9 more
core +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
Researching mobile learning: overview, September 2006 to September 2008 [PDF]
, 2009 This is the summary of the report, which brought together the findings from the third phase of a two-year development and research project that focused on the impact of one-to-one personal ownership of mobile devices.
Ching Yee, Wan +2 more
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FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Review of research and evaluation on improving adult literacy and numeracy skills [PDF]
, 2011 The purposes of this literature review are threefold. First, this review summarises findings of the research from the last decade in six fields identified by the Department for Business, Innovation and Skills (BIS) as critical to its forward planning: (1)
Frearson, Michael +3 more
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