Results 11 to 20 of about 137 (105)

AF4-to-SAXS: expanded characterization of nanoparticles and proteins at the P12 BioSAXS beamline. [PDF]

J Synchrotron Radiat
By coupling asymmetrical‐flow field‐flow fractionation to small‐angle X‐ray scattering (AF4–SAXS), we enable precise, size‐resolved analysis of polydisperse samples. Our automated AF4–SAXS system at the EMBL P12 beamline streamlines workflows, making advanced characterization accessible to both novice and experienced users, with principles adaptable to
Da Vela S, Bartels K, Franke D, Soloviov D, Gräwert T, Molodenskiy D, Kolb B, Wilhelmy C, Drexel R, Meier F, Haas H, Langguth P, Graewert MA.   +12 more
europepmc   +2 more sources

Preface

, 2021
The International Conference on Ocean and Earth Science (ICOES) was held in Jakarta, Indonesia, on 18-20 November 2020 as a part of Indonesian Science Expo (ISE), a scientific event held annually by the Indonesian Institute of Sciences (LIPI). Indonesian

semanticscholar   +1 more source

The Impact of the Central Carbon Energy Metabolism Transcriptome in the Pathogenesis and Outcomes of Multiple Myeloma

Blood, 2021
Introduction: Multiple gene expression profile assays have successfully prognosticated the overall survival (OS) outcomes of patients with Newly Diagnosed Multiple Myeloma (NDMM) and are now available for use in clinical practice. The genes included in
Laura A. Evans, Shaji K. Kumar, Erik Jessen, A. Dispenzieri, P. Kapoor, F. Buadi, D. Dingli, M. Lacy, S. Hayman, N. Leung, Eli Muchtar, R. Warsame, T. Kourelis, S. Russell, Yi Lin, M. Siddiqui, Jin Sung Jang, R. Kyle, S. Rajkumar, M. Gertz, R. Fonseca, W. Gonsalves   +21 more
semanticscholar   +1 more source

PLLA‐Based Block Copolymers via Raft Polymerization—Impact of the Synthetic Route and Activation Mechanism

Macromolecular Chemistry and Physics, Volume 224, Issue 24, December 2023., 2023
Block copolymers from poly(lactic acid) and functional acrylamides are produced via a combination of ring‐opening polymerization and photo‐iniferter reversible addition‐fragmentation chain transfer (PI‐RAFT) polymerization. The synthetic strategy is optimized toward high molecular weights while maintaining low dispersity.
Ahmad Alsawaf, Yuya Kanehira, Alain M. Bapolisi, Ilko Bald, Matthias Hartlieb   +4 more
wiley   +1 more source

The human factor: results of a small‐angle scattering data analysis round robin

Journal of Applied Crystallography, Volume 56, Issue 6, Page 1618-1629, December 2023., 2023
A data‐analysis round robin was performed using four real‐world datasets to quantify the role of the human factor in analysis; the 46 responses show that the analyses by different researchers and laboratories may not be directly comparable, with large reporting inconsistencies in distribution widths and volume fractions.
Brian R. Pauw, Glen J. Smales, Andy S. Anker, Venkatasamy Annadurai, Daniel M. Balazs, Ralf Bienert, Wim G. Bouwman, Ingo Breßler, Joachim Breternitz, Erik S. Brok, Gary Bryant, Andrew J. Clulow, Erin R. Crater, Frédéric De Geuser, Alessandra Del Giudice, Jérôme Deumer, Sabrina Disch, Shankar Dutt, Kilian Frank, Emiliano Fratini, Paulo R. A. F. Garcia, Elliot P. Gilbert, Marc B. Hahn, James Hallett, Max Hohenschutz, Martin Hollamby, Steven Huband, Jan Ilavsky, Johanna K. Jochum, Mikkel Juelsholt, Bradley W. Mansel, Paavo Penttilä, Rebecca K. Pittkowski, Giuseppe Portale, Lilo D. Pozzo, Leonhard Rochels, Julian M. Rosalie, Patrick E. J. Saloga, Susanne Seibt, Andrew J. Smith, Gregory N. Smith, Glenn A. Spiering, Tomasz M. Stawski, Olivier Taché, Andreas F. Thünemann, Kristof Toth, Andrew E. Whitten, Joachim Wuttke   +47 more
wiley   +1 more source

Pharmacodynamic Analysis of CAR-T Cell Persistence in Patients with Hematologic Malignancies Treated with NKTR-255, an IL-15 Receptor Agonist That Enhances CD8 + T-Cells: Preliminary Results from a Phase 1 Study

Blood, 2021
Background: Autologous T cells engineered to express a CD19 or BCMA-specific chimeric antigen receptor (CAR) have shown high overall response rates in treatment-refractory B-cell non-Hodgkin lymphoma (NHL) and BCMA + multiple myeloma (MM), respectively.
C. Turtle, E. Budde, K. Patel, M. Perales, A. Cowan, Hayder Saeed, J. Chavez, A. Hirayama, D. Kirchmeier, M. Janakiram, Kai Wu, L. Fong, Z. Lee, N. Dixit, Xiaoli Wang, K. Kai, M. Marcondes, J. Zalevsky, N. Shah   +18 more
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Thermo‐Responsive Ultrafiltration Block Copolymer Membranes Based on Polystyrene‐block‐poly(diethyl acrylamide)

Macromolecular Materials and Engineering, Volume 308, Issue 11, November 2023., 2023
A novel ultrafiltration membrane based on a polystyrene‐b‐poly(diethyl acrylamide) block copolymer is introduced, where the poly(diethyl acrylamide) block features an lower critical solution temperature in water at 32 °C. The membrane is fabricated via the non‐solvent induced phase separation process and the reversible thermal switching capability of ...
Florian V. Frieß, Frank Hartmann, Lea Gemmer, Jens Pieschel, Bart‐Jan Niebuur, Matthias Faust, Tobias Kraus, Volker Presser, Markus Gallei   +8 more
wiley   +1 more source

Safety, Tolerability, PK/PD and Preliminary Efficacy of NKTR-255, a Novel IL-15 Receptor Agonist, in Patients with Relapsed/Refractory Hematologic Malignancies

Blood, 2021
Introduction: NKTR-255, an investigational novel polymer-conjugated recombinant human interleukin (IL)-15 agonist, maintains the full spectrum of IL-15 biology and provides sustained pharmacodynamic (PD) responses without the need for daily dosing ...
N. Shah, A. Tan, E. Budde, C. Hofmeister, A. Cowan, M. Perales, T. Choi, Hayder Saeed, J. Chavez, J. Ye, M. Cairo, D. Rizzieri, G. Orloff, Z. Lee, N. Dixit, Wildaliz Nieves, Qiang Zhao, Xiaoli Wang, K. Kai, M. Marcondes, M. Tagliaferri, J. Zalevsky, K. Patel   +22 more
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rTMS ameliorates depressive‐like behaviors and regulates the gut microbiome and medium‐ and long‐chain fatty acids in mice exposed to chronic unpredictable mild stress

CNS Neuroscience &Therapeutics, Volume 29, Issue 11, Page 3549-3566, November 2023., 2023
rTMS (15 Hz, 1.26 T) alleviates depressive‐like behavior of CUMS‐treated mice and regulates the flora represented by Cyanobacterium and Actinobaciota. Meanwhile, it improves polyunsaturated fatty acids (PUFAs) in hippocampus and PFC, and also upregulates C20:4N6, C20:5N3 and C20:3N3 PUFAs in the plasma.
Cui‐Hong Zhou, Yi‐Huan Chen, Shan‐Shan Xue, Qing‐Qing Shi, Lin Guo, Huan Yu, Fen Xue, Min Cai, Hua‐Ning Wang, Zheng‐Wu Peng   +9 more
wiley   +1 more source

Fabrication of Patchy Silica Microspheres with Tailor‐Made Patch Functionality using Photo‐Iniferter Reversible‐Addition‐Fragmentation Chain‐Transfer (PI‐RAFT) Polymerization

Small, Volume 19, Issue 43, October 25, 2023., 2023
Patchy silicon dioxide microspheres are fabricated via a solid‐state supported microcontact printing (µCP) routine. The amino functions introduced during the µCP process are used as anchor groups to graft tailor‐made polymeric materials from the patch area using photo‐iniferter reversible addition‐fragmentation chain‐transfer (RAFT) polymerization. The
Pinar Akarsu, Stefan Reinicke, Anne‐Catherine Lehnen, Marek Bekir, Alexander Böker, Matthias Hartlieb, Martin Reifarth   +6 more
wiley   +1 more source