Results 21 to 30 of about 269 (111)

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Comparative effects of superheated steam and hot air roasting on the in vitro phospholipase A2 inhibitory activity and polyphenol composition of cocoa beans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Cocoa, derived from Theobroma cacao, is a popular food ingredient used to produce chocolate. Cocoa is rich in polyphenols and human and laboratory model studies have indicated that cocoa and chocolate can mitigate chronic inflammatory conditions.
Sawali Navare, Bethany H. Lam, Misha T. Kwasniewski, Ramaswamy Anantheswaran, Joshua D. Lambert   +4 more
wiley   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

The Arrival of Exome Sequencing in French Prenatal Diagnosis: An Exploratory Qualitative Study Among Professionals in Prenatal Diagnosis Centers: Prenatome‐SHS

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Following the first French multicenter pilot study (AnDDI‐Prenatome) focused on the implementation of prenatal exome sequencing (pES), this ancillary study aims to explore the ethical and clinical issues raised by pES within multidisciplinary prenatal diagnosis centers.
Charlène Daval, Nicolas Meunier‐Beillard, Eléonore Viora‐Dupont, Julian Delanne, Aurore Garde, Caroline Racine, Frédéric Tran Mau‐Them, Anne‐Sophie Denommé‐Pichon, Christophe Philippe, Ange‐Line Bruel, Hana Safraou, Sylvie Odent, Chloé Quélin, Marine Legendre, Sophie Naudion, Médéric Jeanne, Marie‐Line Jacquemont, Agnès Guichet, Camille Saldana, Anne‐Marie Guerrot, Alice Goldenberg, Caroline Guégan, Marie Vincent, Audrey Putoux, Christine Francannet, Constance Wells, Chloé Arthuis, Elodie Alexandre, Thierry Rousseau, Olivia Martz, Emilie Simon, Ornella Magnien, Fanny Bobert, Sophie Bert, Frédéric Coatleven, Fanny Reveyaz, Perrine Moulinié, Christine Binquet, Christel Thauvin‐Robinet, Laurence Faivre   +39 more
wiley   +1 more source

A manifesto for plant science education

PLANTS, PEOPLE, PLANET, EarlyView.
Plants provide oxygen, food, shelter, medicines and environmental services, without which human society could not exist. Tackling pressing and global challenges requires well‐trained plant scientists and plant‐aware individuals. This manifesto provides a practical evidence‐based vision to strengthen plant science education, focussed on five strategic ...
Elizabeth Alvey, Andrea Paterlini, Mary E. Williams, Mia E. Cerfonteyn, Samantha Dobbie, Steven Dodsworth, Sonja D. Dunbar, Lauren R. Headland, Anastasia Kolesnikova, Pankaj Kumar, Silvia Manrique, Catherine Mansfield, Sebastian Stroud, Shannon Woodhouse, Hailey Ashton, Yoselin Benitez‐Alfonso, Emily Breeze, Kelsey J. R. P. Byers, Chana P. Chetariya, Beth C. Dyson, Alec Forsyth, Beatriz Gonçalves, Camila Gonzalez, Daniel M. Jenkins, Joanna Kacprzyk, Kirsten Knox, George R. Littlejohn, Sara Lopez‐Gomollon, Enrique López‐Juez, Claudia Martinho, Vincent D. P. Modji, Itumeleng Moroenyane, Amy S. Newell, Geraint J. Parry, Julie Peacock, Anne Plessis, Bushra Saeed, Luis Sanz, Steven H. Spoel, Laurel R. Tully, Laura Turchi, Helen K. Woodfield, Katharine E. Hubbard   +42 more
wiley   +1 more source

Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil

Veterinary Record, EarlyView.
Abstract Background Leptospirosis is a significant zoonosis in tropical regions, where poor sanitation and favourable climate aid its spread. Synanthropic animals such as the cane toad (Rhinella jimi), which share environments with both people and wild and domestic animals, may harbour Leptospira and contribute to urban and rural transmission cycles ...
Karla N. de Souza Rocha, Aline de Lima Peixoto, Lucila S. de Medeiros Pereira, Debora Ferreira Cardoso, Maria L. C. Rodrigues Silva, Sérgio S. de Azevedo, Juliana P. F. de Oliveira, Clebert J. Alves, Mozar Alves Fonseca, Severino S. dos Santos Higino   +9 more
wiley   +1 more source

Imperative for a health‐centred focus on climate change in radiology

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Summary Climate change negatively impacts individual and population‐level health through multiple pathways, including poor air quality, extreme heat and changes in infectious disease. These health effects will lead to higher health system and medical imaging utilisation.
Omar Taboun, Chloe DesRoche, Kate Hanneman   +2 more
wiley   +1 more source

Sustainability in Radiology: Position Paper and Call to Action From ACR, AOSR, ASR, CAR, CIR, ESR, ESRNM, ISR, IS3R, RANZCR, and RSNA

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT The urgency for climate action is recognised by international government and healthcare organisations, including the United Nations (UN) and World Health Organisation (WHO). Climate change, biodiversity loss, and pollution negatively impact all life on earth. All populations are impacted but not equally; the most vulnerable are at highest risk,
Andrea G. Rockall, Bibb Allen, Maura J. Brown, Tarek El‐Diasty, Jan Fletcher, Rachel F. Gerson, Stacy Goergen, Amanda P. Marrero González, Thomas M. Grist, Kate Hanneman, Christopher P. Hess, Evelyn Lai Ming Ho, Dina H. Salama, Julia Schoen, Sarah Sheard   +14 more
wiley   +1 more source

Reliability, agreement and variability of a markerless computer vision algorithm for equine gait analysis under field conditions

Equine Veterinary Journal, EarlyView.
Abstract Background Computer vision‐based algorithms offer accessible alternatives for equine gait analysis but require thorough assessment under diverse conditions. Objectives To evaluate a proprietary vision‐based algorithm's reliability in measuring vertical displacement signals (VDS) at the eye, withers and croup, alongside groundline estimation ...
Karsten Key, Katja Berg, Jakob Kirkegaard, Kristian Ringkjær Andresen, Sabrina Skov Hansen   +4 more
wiley   +1 more source