Results 1 to 10 of about 309 (119)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Advances in Hybrid Icing and Frosting Protection Strategies for Optics, Lens, and Photonics in Cold Environments Using Thin‐Film Acoustic Waves

Advanced Engineering Materials, EarlyView.
This article provides a comprehensive overview of fundamentals and recent advances of transparent thin‐film surface acoustic wave technologies on glass substrates for monitoring and prevention/elimination of fog, ice, and frost. Fogging, icing, or frosting on optical lenses, optics/photonics, windshields, vehicle/airplane windows, and solar panel ...
Hui Ling Ong, Zhangbin Ji, Luke Haworth, Yihao Guo, Jaime del Moral, Stefan Jacob, Ana Borras, Agustin R. Gonzalez‐Elipe, Jikai Zhang, Jian Zhou, Glen McHale, Yong‐Qing Fu   +11 more
wiley   +1 more source

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal‐Phenolic Networks

Advanced Healthcare Materials, EarlyView.
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima   +8 more
wiley   +1 more source

Capillary‐Driven 3D Open Fluidic Networks for Versatile Continuous Flow Manipulation

Advanced Materials, EarlyView.
The capillary‐driven 3D open fluidic networks (OFNs), composed of connected polyhedral frames, enable precise, programmable, and versatile manipulation of unary, binary, and multiple continuous flows in both spatial and temporal dimensions. OFNs represent a significant leap beyond conventional microfluidics, unlocking new possibilities for selective ...
Shuangmei Wu, Siqi Sun, Jia Ye, Liqiu Wang, Yiyuan Zhang   +4 more
wiley   +1 more source

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan, Cheng‐Hung Luo, Wen‐Ling Lin, Liu‐Chun Wang, Divinah Manoharan, Po‐Ya Chang, Hwo‐Shuenn Sheu, Chen‐Hao Yeh, Chia‐Jui Yen, Chen‐Sheng Yeh   +9 more
wiley   +1 more source

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin, Jackson K. Flowers, Tobias H. Piotrowiak, Frederic Felsen, Leon Merker, Alfred Ludwig, Dominic Bresser, Helge Sören Stein   +7 more
wiley   +1 more source

Homelessness Service Usage Patterns of 30,000 Homeless and At‐Risk Households: The Melbourne Access Point Study

Australian Journal of Social Issues, EarlyView.
ABSTRACT Over the last three decades, overseas researchers have utilised administrative data to identify distinct patterns in shelter use. In Australia, the use of administrative data to understand service utilisation patterns among people ‘at risk’ of homelessness and experiencing homelessness is limited.
Godwin Kavaarpuo, Kathryn Daley, Guy Johnson   +2 more
wiley   +1 more source

Linking students' grit and academic engagement: Mediating role of academic motivation and self‐regulated learning

British Educational Research Journal, EarlyView.
Abstract The study investigated the relationships between students' grit, academic engagement, motivation and self‐regulated learning (SRL). It explored the mediating role of academic motivation and SRL in the relationship between students' grit and academic engagement.
Paul Obeng, Medina Srem‐Sai, Iddrisu Salifu, Mustapha Amoadu, Francis Arthur, Edmond Kwesi Agormedah, John Elvis Hagan Jr, Thomas Schack   +7 more
wiley   +1 more source

Oxidative Folding of a Two‐Chain Protein Having Three Interchain Disulfide Bonds. Synthesis of Bromelain Inhibitor VI Through Native Chain Assembly

Chemistry – A European Journal, EarlyView.
Bromelain inhibitor VI, a two‐chain protein stabilized by three interchain SS bonds and two intrachain SS bonds, was synthesized in an incredibly high isolated yield (53%) just by mixing the two native chains in a buffer solution. This success made a record of oxidative protein folding for the most complicated and difficult one.
Michio Iwaoka, Sawa Akaboshi
wiley   +1 more source

A Roadmap for Biomass‐Driven Development of Sustainable Phase Change Materials

ChemSusChem, EarlyView.
This comprehensive review advances the scientific understanding of sustainability and circularity in phase change material (PCM) fabrication by providing a strategic framework for developing composites from abundant, renewable resources. By screening biomass‐derived PCMs, carbons, and biopolymers, a roadmap is outlined for the development of ...
Alina Brzęczek‐Szafran, Magdalena Gwóźdź, Nicolas Brun, Marcin Wysokowski, Karolina Matuszek   +4 more
wiley   +1 more source