Results 81 to 90 of about 1,249,970 (217)

Normality and the Higher Numerical Range

, 1978
Let Mn(C) be the vector space of all w-square complex matrices. Denote by (• , •) the standard inner product in the space C n of ...
Benjamin N. Moyls, Marvin Marcus, Ivan Filippenko   +2 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

On the convexity of the quaternionic essential numerical range [PDF]

The numerical range in the quaternionic setting is, in general, a non-convex subset of the quaternions. The essential numerical range is a refinement of the numerical range that only keeps the elements that have, in a certain sense, infinite multiplicity.
Diogo, C., Mendes, S., Soares, H., Carvalho, L.   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Numerical approximation of the boundary of numerical range of matrix polynomials

, 2005
The numerical range of an n×n matrix polynomial P (λ) = Amλm+ Am−1λm−1 + · · ·+A1λ+A0 is defined by W (P) = {λ ∈ C: x∗P (λ)x = 0, x ∈ Cn, x∗x = 1}, and plays an important role in the study of matrix polynomials.
Charalampos Tsitouras, Tsitouras, C, Psarrakos, P, Panayiotis Psarrakos   +3 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Proof of concept of diffuse optical tomography using time-of-flight range imaging cameras

, 2010
Diffuse optical tomography is an optical technique to create 3-dimensional images of the inside of highly scattering material. Research groups around the world have been developing imaging systems using various source-detector arrangements to determine ...
Ahmad Hassan, Dorrington, Adrian A., Payne, Andrew D., Hassan, Ahmad, Künnemeyer, Rainer, Adrian Dorrington, Andrew Payne, Rainer Künnemeyer   +7 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source