Results 31 to 40 of about 25,265,347 (168)

On H-hyper Connected Spaces [PDF]

open access: yes, 2019
In this paper, we define H-hyper connected spaces in generalized topological spaces with hereditary class H and we prove the characterizations of H-hyper connected spaces using open, rare and open sets.
Devi, P. Vimala
core  

Local rigidity of infinite-dimensional Teichmüller spaces [PDF]

open access: yes, 2006
This paper presents a rigidity theorem for infinite-dimensional Bergman spaces of hyperbolic Riemann surfaces, which states that the Bergman space $A^{1}(M)$, for such a Riemann surface $M$, is isomorphic to the Banach space of summable sequence, $l^{1}$.
Fletcher, A. (Alastair)
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Hopf spaces /

open access: yes, 1976
Includes bibliographical references (pages 211-218) and index.Print version record.Front Cover; Hopf Spaces; Copyright Page; Table of Contents; Introduction; Chapter 0.
Zabrodsky, Alexander.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

[Report to W. P. Gannaway by P. M. Parks and M. H. Brumley, February 17, 1964 #1]

open access: yes, 1964
Criminal intelligence report by P. M. Parks and M. H. Brumley regarding an interview with Eddie Piper. Piper, who worked at the Texas School Book Depository, stated that he saw Lee Harvey Oswald when he came in to work at 10 AM. He did not observe Oswald
Dallas (Tex.). Police Department.
core  

Norms of certain operators on weighted L-spaces and Lorentz sequence spaces. [PDF]

open access: yes, 2002
The problem addressed is the exact determination of the norms of the classical Hilbert, Copson and averaging operators on weighted spaces and the corresponding Lorentz sequence spaces , with the power weighting sequence or the variant defined by .
Jameson, Graham J. O., Lashkaripour, R.
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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