Results 41 to 50 of about 10,706 (218)
COWS: A Timed Service-Oriented Calculus
, 2007 COWS (Calculus for Orchestration of Web Services) is a foundational language for Service Oriented Computing that combines in an original way a number of ingredients borrowed from well-known process calculi, e.g.
R. Pugliese +7 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A STUDY ON SOME NEW RESULTS ARISING FROM (p, q)-CALCULUS
, 2020 This paper includes some new investigations and results for post quantum calculus, denoted by (p, q)-calculus. A chain rule for (p, q)-derivative is given. Also, a new (p, q)-analogue of the exponential function is introduced and its properties including
Araci, Serkan +2 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Extended p-adic q-invariant integrals on ℤp associated with applications of umbral calculus
, 2013 The fundamental aim of this paper is to consider some applications of umbral calculus by utilizing from the extended p-adic q-invariant integral on ℤp.
Araci, Serkan +2 more
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, 2021 In this paper, we establish some new Hermite–Hadamard type inequalities for preinvex functions and left-right estimates of newly established inequalities for p,q-differentiable preinvex functions in the context of p,q-calculus.
Jarunee Soontharanon +5 more
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On (p,q)-Bernoulli, (p,q)-Euler and (p,q)-genocchi polynomials
, 2016 In the present paper, we introduce a new kind of Bernoulli, Euler and Genocchi polynomials based on the (p,q)-calculus and investigate their some properties involving addition theorems, difference equations, derivative properties, recurrence ...
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