Results 91 to 100 of about 18,773,992 (242)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Strengthening enterprise competitiveness by synchronizing supply chain
When competition is fierce and many producers try to create a competitive advantage by lowering prices, price wars are very common, but only few survive. Low prices erode producers’ margins and economic viability of the company. Low prices are very short-
Rimvydas Jasinavičius +1 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
ORGANISASI INTERNASIONAL LANJUTAN G-20 menjadi salah satu kajian dalam organisasi internasional lanjutan, karena merupakan sebuah komunitas ekonomi baru dunia, yang terdiri dari negara-negara industri maju dan negara berkembang yang dianggap memiliki ...
Triwahyuni, Dewi
core
The Critical Role of G-20 in Dealing with the 2008 Global Financial Crisis [PDF]
Strategi G-20 dalam mengatasi krisis keuangan telah dinyatakan pada kesepakatan KTT G-20 2008-2009 dengan adanya tiga pertemuan selama periode tersebut berlangsung (Washington, London dan Pittsburgh). Bersama dengan beberapa lembaga termasuk IMF, WB, FSB,
Priangani, A. (Ade) +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Problems of public sector accounting and financial reporting standards implementation into practice
This article analyzes process of realization in practice and problems faced by accountants in implementation of Accounting and Financial Statement System Reform in the Public Sector which currently takes place in the European Union and other developed ...
Jovita Bikienė
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Warren G. Harding letter to John R. Shillady, February 20, 1920
In this letter dated February 20, 1920, Senator Warren G. Harding writes to John R. Shillady of New York in response to his letter of February 18. Harding states that he supports the advancement of African Americans, and claims that the Republican Party ...
Harding, Warren G. (Warren Gamaliel), 1865-1923
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

