Results 121 to 130 of about 23,383,453 (236)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Napoli, Biblioteca Nazionale «Vittorio Emanuele III», S.Q. XIII G 20
Scheda catalografica dell'incunabolo con segnatura S.Q.
Martina Caronte
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A crise financeira de 2008 teve impactos significativos no capitalismo global, sendo um de seus reflexos na estrutura da governança global a constituição e evolução do G-20. Neste contexto, o objetivo do artigo é analisar tais mudanças e, em especial, as
Leonardo Ramos +3 more
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Análise Multivariada de Indicadores Socioeconômicos dos Países do G-20
This study presents an analysis on the socio-economic indicators of the G-20 countries by principal components and cluster analysis, in order to detect associations or similarities between the nations. The results concerning variables that characterize
Gil Bracarense Leite +2 more
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Letter: Mary G. Smith to Ida M. Tarbell, June 20, 1918
Handwritten letter of three pages, signed (Mrs.
Smith, Mary G. [Mrs. E.G.]
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
John Galvin letter to Warren G. Harding, January 20, 1920
In this letter dated January 20, 1920, Cincinnati Mayor Jon Galvin writes to Senator Warren G. Harding expressing his gratitude for being selected as one of his delegates to the Republican National Convention.
Galvin, John, 1862-1922
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