Results 41 to 50 of about 8,095,089 (249)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

The Late Reionization of Filaments

, 2009
We study the topology of reionization using accurate three-dimensional radiative transfer calculations post-processed on outputs from cosmological hydrodynamic simulations.
Abel, Ahn, Aubert, Barkana, Barkana, Benjamin D. Oppenheimer, Bolton, Bouwens, Bruzual, Chabrier, Choudhury, Ciardi, Ciardi, Dav��, Dav��, Fan, Faucher-Gigu��re, Feryal ��zel, Finlator, Finlator, Finlator, Furlanetto, Gnedin, Gnedin, Gnedin, Haiman, Hinshaw, Iliev, Iliev, Iliev, Kennicutt, Kennicutt, Komatsu, Kristian Finlator, Lee, Lidz, McKee, McQuinn, Miralda-Escud��, Mortonson, Nakamoto, Oey, Oh, Okamoto, Oppenheimer, Oppenheimer, Oppenheimer, Romeel Dav��, Schleicher, Shin, Shull, Springel, Springel, Springel, Storrie-Lombardi, Sutherland, Tasitsiomi, Thoul, Trac, Trac, Wise, Wise   +61 more
core   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation

BMC Cancer, 2021
Background This study describes post-treatment work patterns in lymphoma survivors treated with high-dose chemotherapy with autologous stem-cell transplantation (HDT-ASCT).
Kjersti Helene Hernæs, Knut B. Smeland, Unn-Merete Fagerli, Cecilie E. Kiserud   +3 more
doaj   +1 more source

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

Pediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard, Anni Young Lundgaard, Laura Ann Rechner, Danijela Dejanovic, Hanne Krogh Rose, Jolanta Hansen, Leila Vaalavirta, Miia Mokka, Marianne Aznar, Peder Skov Wehner, Lisa Lyngsie Hjalgrim, Maja Vestmø Maraldo   +11 more
wiley   +1 more source

A cross-sectional study of current work ability after radical prostatectomy

BMC Urology, 2020
Background Work ability represents a person’s subjective assessment of current ability to work compared to his lifetime best. Since many men with prostate cancer are retired, work ability represents a more relevant work measure than employment status ...
Alv A. Dahl, Bjørn Brennhovd, Sophie D. Fosså, Karol Axcrona   +3 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Development of a protocol complexity tool: a framework designed to stimulate discussion and simplify study design

BMC Medical Research Methodology
Background Over the last decade, the pharmaceutical industry has witnessed longer, more complex, and expensive clinical trials. This complexity contributes to delays in clinical trial implementation, execution, monitoring, recruitment, data cleaning, and
Bartholomeus J.A. Willigers, Agata E Wiesiolek, Bruce Potter, Alina Pszczółkowska, Cecilia Kristensson , Veronica Presz , Gabriela Luporini Saraiva, Ioannis Psallidas   +7 more
doaj   +1 more source

Asymptotic tails of massive scalar fields in a stationary axisymmetric EMDA black hole geometry

, 2004
The late-time tail behavior of massive scalar fields is studied analytically in a stationary axisymmetric EMDA black hole geometry. It is shown that the asymptotic behavior of massive perturbations is dominated by the oscillatory inverse power-law ...
Abramowitz M, Giammatteo M, Hod S, Hod S, Hod S, Hod S, Hod S, Jing J L, Jing J L, Jing Ji-Liang, Khanna G, Leaver E W, Misner C W, Morse P M, Pan Qi-Yuan, Price R H, Ruffini R   +16 more
core   +1 more source

Non-zero torsion and late cosmology

, 2020
In this work, we study some thermodynamical aspects associated with torsion in a flat FLRW spacetime cosmic evolution. By implementing two Ansatze for the torsion term, we find that the model admits a phantom regime or a quintessence behavior.
Cruz, Miguel, Izaurieta, Fernando, Lepe, Samuel   +2 more
core   +1 more source