Results 181 to 190 of about 2,851,390 (300)

Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa. [PDF]

PLOS Glob Public Health
Thomas KA, Okoro C, Ntshiqa T, Damovsky V, Goldberg D, Ramokhoase O, Clark RA, Jassat W, Churchyard GJ, Abdullah F, Kubjane M, Seeley J, Charalambous S, White RG.   +13 more
europepmc   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Post-traumatic stress disorder among children and adolescents affected by armed conflict in East Africa: a systematic review and meta-analysis. [PDF]

BMJ Paediatr Open
Adugna A, Abebe GF, Alie MS, Girma D.
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Piloting the feasibility of a population-based joint TB-HIV survey in KwaZulu-Natal Province, South Africa, 2019. [PDF]

PLOS Glob Public Health
Murangandi P, Oladimeji O, Zungu N, Makola L, Marinda E, Simbayi L, Zuma K, Ramlagan S, Jooste S, Maseko G, Naidoo I, Nwosu C, McCracken S, Moyo S, Hladik W.   +14 more
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

A Scoping Review of African Health Histories from the Pre-Colonial to SDG Eras: Insights for Future Health Systems. [PDF]

Healthcare (Basel)
Karamagi H, Iwu-Jaja C, Mazingisa AV, Adamu AA, Oduwole EO, Mamo A, Sy S, Wiysonge CS.   +7 more
europepmc   +1 more source

Mobile Phones and Economic Development in Africa

, 2010
J. Aker, I. Mbiti
semanticscholar   +1 more source

¿Dónde está África? [PDF]

, 2012
Mary Luz Estupiñán Serrano
core  

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source