Results 41 to 50 of about 521,624 (218)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Composición, estructura y diversidad del cerro El Águila, Michoacán, México Composition, structure and diversity of the cerro El Águila, Michoacán, Mexico

Revista Mexicana de Biodiversidad, 2011
Se describe la composición, estructura y diversidad de la vegetación presente en el cerro El Águila, Michoacán. Se reconocieron fisonómicamente 5 tipos de vegetación y en cada uno se establecieron 16 parcelas circulares de 400 m² (3.2 ha) para censar los
Luis Eduardo Zacarias-Eslava, Guadalupe Cornejo-Tenorio, Jorge Cortés-Flores, Nahú González-Castañeda, Guillermo Ibarra-Manríquez   +4 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Relación entre suelos y estructura del bosque en la Amazonía colombiana

Revista de Biología Tropical, 2011
Las diferencias estructurales del bosque pueden ser el producto de variaciones ambientales a diferentes escalas, entre ellas los suelos. Para evaluar tal asociación, se usaron los datos de estructura del bosque y de suelos de una parcela de 6ha ...
Bayron R Calle-Rendón, Flavio Moreno, Dairon Cárdenas-López   +2 more
doaj   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

CRESCIMENTO E BIOMASSA DE INDIVÍDUOS JOVENS DE Cabralea canjerana (Vell.) Mart.

BIOFIX Scientific Journal, 2018
Este trabalho possui como objetivo ajustar e selecionar modelos matemáticos capazes de estimar o incremento periódico em área basal, o volume e biomassa de indivíduos jovens de Cabralea canjerana (Vell.) Mart.
Karina Lanzarin, Frederico Dimas Fleig, Evandro Alcir Meyer, Lilian Daniel Pereira, Thomas Schöder, Gerson Santos Lisboa   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source