The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang +6 more
wiley +1 more source
Evolving Molecular Subtypes of Gastric Cancer: From Past Classifications to Present Consensus and Future Directions for Precision Therapy. [PDF]
Lee JS.
europepmc +1 more source
Biogeographic Regions Within Indomalaya: An Integrated Approach Using Bird Distributions
ABSTRACT Aim Biogeographic regions define areas of shared species distributions and provide a framework for testing evolutionary hypotheses. Recent quantitative methods have improved the delineation of these regions, but each relies on assumptions about how species distributions are summarised and varies in sensitivity to spatial scale.
Zheng Oong +2 more
wiley +1 more source
Construction and Validation of a Model for Predicting Cervical Intraepithelial Neoplasia Grade II+: A Cross-Sectional Population Study via Machine Learning. [PDF]
He J +8 more
europepmc +1 more source
Clustered Land Restoration Projects Increase Cloud Formation in West African Drylands
Abstract Land restoration projects are implemented across Africa to combat land degradation and climate change. By changing the vegetation cover, these projects can potentially impact cloud formation through changes in energy and water partitioning between the Earth's surface and the atmosphere.
J. Ruijsch +4 more
wiley +1 more source
Machine learning in early screening for high-grade cervical intraepithelial neoplasia using blood testing. [PDF]
Yue C +5 more
europepmc +1 more source
A Unified Theory for the Global Thunderstorm Distribution and Land–Sea Contrast
Abstract This article evaluates Entraining CAPE (ECAPE) as a thunderstorm proxy in climate studies using Global Precipitation Measurement satellite observations. ECAPE modifies traditional CAPE to account for the dependence of entrainment on the vertical wind shear, the lifted condensation level (LCL) height, and the properties of a cloud's surrounding
John M. Peters +4 more
wiley +1 more source
Multifunctional biofunctionalized hybrid nanoantifungals with novel active coating agents based on cinnamaldehyde- and β-cyclocitral-modified polydopamine. [PDF]
García-Simarro MP +7 more
europepmc +1 more source

