Results 61 to 70 of about 919,444 (247)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

La chaire UNESCO HÉN devient « accessibilité universelle, éducation et numérique » : questions de recherche et objectifs stratégiques

open access: yes
International audienceLa chaire UNESCO HÉN (Handicap, Éducation et Numérique) change de nom et vise à produire, développer et évaluer des ressources numériques innovantes favorisant l’objectif d’une éducation et d’une société plus inclusive en France et ...
Epstein, Muriel
core   +2 more sources

Analysis of Inclusive Education Policy Implementation in Developing Countries

open access: yesEdukasia
Inclusive education is a global movement that emerged in response to the exclusion of learners who are viewed as different by the education system. Countries that hold the consensus to implement inclusive education have structured their legislation to ...
Umi Khoiriyah   +4 more
doaj   +1 more source

SUPPORT IN INCLUSIVE EDUCATION

open access: yesHuman Research in Rehabilitation, 2016
In order for inclusive class to be successful, associates are of great help to teachers. Besides associates, teachers' specialization can be accomplished through educational seminars on the inclusion topic. However, information about inclusion, working
Belma Čičkušić   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Inclusive Education in Armenia

open access: yesArmenian Folia Anglistika, 2019
The article is on the Inclusive Education in general and the status of it in the Republic of Armenia. It mainly covers the notion of Inclusive Education, the functioning model of education in Armenia, its necessity and importance to be applied in many ...
Syuzanna Tadevosyan
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Pre-service teachers' empathy and attitudes toward inclusive education-The chain mediating role of teaching motivation and inclusive education efficacy.

open access: yesPLoS ONE
Recently, inclusive education has become the direction of special education development. Inclusive education requires that teachers' educational philosophies and approaches meet the needs of all students.
Nana Jiang   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Framing heuristics in inclusive education: The case of Uganda’s preservice teacher education programme

open access: yesAfrican Journal of Disability, 2019
Background: Recent education-related research has raised concerns about the persistent exclusion of vulnerable learners in Uganda. The Revised Primary Teacher Education Curriculum of 2013 marked an ambitious yet inconclusive attempt to advance the ...
Proscovia S. Nantongo
doaj   +1 more source

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