Results 41 to 50 of about 2,407 (188)

Telomere length and mitochondrial DNA copy number in bipolar disorder: identification of a subgroup of young individuals with accelerated cellular aging

open access: yesTranslational Psychiatry, 2022
The 10–15-years decrease in life expectancy observed in individuals with bipolar disorder (BD) has been linked to the concept of accelerated cellular aging. Telomere length (TL) and mitochondrial DNA copy number (mtDNAcn) have been proposed as markers of
L. Spano   +7 more
doaj   +1 more source

Comprehensive Measurement‐Based Assessment of Downlink RF‐EMF Exposure in Urban Environments: Multi‐Method Analysis and Intercomparison

open access: yesBioelectromagnetics, Volume 46, Issue 8, December 2025.
ABSTRACT This paper presents a comprehensive measurement‐based assessment of radio‐frequency (RF) electromagnetic field (EMF) exposure level in a French city. Three types of assessment methods are used to collect measurement data: drive test (DT), spot measurements, and sensor networks. The DT measurements were conducted by a portable spectrum analyzer,
Shanshan Wang   +8 more
wiley   +1 more source

Stakeholder perspectives and experiences of the implementation of remote mental health consultations during the COVID-19 pandemic: a qualitative study

open access: yesBMC Health Services Research, 2023
Background Remote mental health consultations were swiftly implemented across mental health services during the COVID-19 pandemic. Research has begun to inform future design and delivery of telemental health services.
Emer Galvin   +8 more
doaj   +1 more source

Bipolar Early Intervention Using New Digital Technologies (BLEND): A Pilot Randomised Controlled Trial of a Novel Blended‐Digital Early Intervention Model of Care for Youth With Bipolar Disorder I or II

open access: yesEarly Intervention in Psychiatry, Volume 19, Issue 6, June 2025.
ABSTRACT Background Despite evidence for early interventions for bipolar disorder (BD), there are relatively few accessible treatment models. We developed a digitally augmented model of care termed BLEND (BipoLar early interventions using New Digital technologies) which aims to improve mood symptoms in BD.
Aswin Ratheesh   +17 more
wiley   +1 more source

Existence of solutions for quasilinear elliptic equations with nonlinear boundary conditions and indefinite weight

open access: yesElectronic Journal of Differential Equations, 2012
In this article, we establish the existence and non-existence of solutions for quasilinear equations with nonlinear boundary conditions and indefinite weight. Our proofs are based on variational methods and their geometrical features.
Guoqing Zhang   +2 more
doaj  

Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

open access: yesBMC Psychiatry, 2022
Background Bipolar Disorder (BD) is a complex mental disease characterized by recurrent episodes of mania and depression. Lithium (Li) represents the mainstay of BD pharmacotherapy, despite the narrow therapeutic index and the high variability in ...
Nadia Cattane   +8 more
doaj   +1 more source

Attitudes of medical students towards conflict of interest: a national survey in France.

open access: yesPLoS ONE, 2014
Following recent health scandals in France, the French parliament adopted law n°2011-2012 to regulate ties between physicians and the pharmaceutical industry.
Bruno Etain   +4 more
doaj   +1 more source

Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs

open access: yesPharmaceutics, 2023
Drug-metabolizing enzymes and drug transporters are key determinants of drug pharmacokinetics and response. The cocktail-based cytochrome P450 (CYP) and drug transporter phenotyping approach consists in the administration of multiple CYP or transporter ...
Léa Darnaud   +13 more
doaj   +1 more source

Does BioAge identify accelerated aging in individuals with bipolar disorder? An exploratory study in the FACE‐BD cohort

open access: yesBipolar Disorders, Volume 26, Issue 6, Page 595-603, September 2024.
Abstract Background Individuals with bipolar disorders (BD) have an estimated loss of life expectancy around 10–15 years. Several laboratory‐measured biomarkers of accelerated aging exist (e.g., telomere length), however with a questionable transferability to bedside.
Bruno Etain   +102 more
wiley   +1 more source

Bipolar disorder and cumulative trauma: A systematic review of prevalence and illness outcomes

open access: yesJournal of Clinical Psychology, Volume 80, Issue 3, Page 692-713, March 2024.
Abstract Background The experience of cumulative trauma may be common in bipolar disorder (BD). However, it is not frequently reported as most studies focus on childhood trauma without examining differences in the amount of trauma experienced. This systematic review aimed to determine the prevalence of lifetime cumulative trauma in BD as well as ...
Amy‐Leigh Rowe   +2 more
wiley   +1 more source

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