Results 11 to 20 of about 6,317 (146)

Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis. [PDF]

open access: yesAngew Chem Int Ed Engl, 2022
Kinetic target‐guided synthesis and optimisation led to the first nanomolar ERAP2 inhibitors with outstanding selectivity. The binding modes of the most potent inhibitors were elucidated by X‐ray crystallography. Our frontrunners engage target in cells and display good in vitro and in vivo pharmacokinetic properties.
Camberlein V   +28 more
europepmc   +3 more sources

Electrochemical Characteristics of Lignin in CTMP for Paper Battery Electrodes. [PDF]

open access: yesChemSusChem
Lignin naturally present in papers made of unbleached mechanical pulps is electrochemically active. Here, softwood chemi‐thermomechanical pulp (CTMP) is studied as an active cathode material for application in paper batteries. Proof‐of‐concept measurements are shown, and it is found that softwood CTMP fines exhibit competing oxidative electrochemical ...
Isacsson P   +4 more
europepmc   +2 more sources

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

open access: yesMass Spectrometry Reviews, Volume 42, Issue 5, Page 1984-2206, September/October 2023., 2023
Abstract This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020.
David J. Harvey
wiley   +1 more source

In enemy hands: the Byzantine experience of captivity between the seventh and tenth centuries

open access: yesEarly Medieval Europe, Volume 31, Issue 3, Page 430-458, August 2023., 2023
The present paper deals with forced migration experienced by subjects of the Byzantine Empire captured by foreign enemies in the context of warfare between the seventh and the tenth centuries. The focus of the first part is on the scenarios faced by individuals and groups when an enemy had taken control of a settlement or a larger territory. The second
Grigori Simeonov
wiley   +1 more source

Confessional Intelligence: Early Modern Papal Diplomats and Information‐Gathering Regarding England and Poland

open access: yesHistory, Volume 108, Issue 381, Page 282-302, June 2023., 2023
Abstract This essay examines the information‐gathering practices of papal nuncios and legates to argue that they performed much of the same intelligence work, and in a similar manner, as other diplomatic agents in the early modern Europe. It focuses in particular on papal diplomats’ efforts to gather information regarding two areas that proved ...
CHARLES R. KEENAN
wiley   +1 more source

Of Signs: Matter and Revelation in the Liturgies of William Durand and John Calvin

open access: yesInternational Journal of Systematic Theology, Volume 25, Issue 2, Page 190-206, April 2023., 2023
Abstract This article seeks to set aside what we might call Cartesian physics to revisit William Durand's conception of sign as set forth in the Rationale divinorum officiorum and John Calvin's as set forth in the Institutio christianae religionis. Reading the two works through the lens of medieval physics reveals commonalities – both held signs to be ...
Lee Palmer Wandel
wiley   +1 more source

The building projects and the Histories of Gregory of Tours

open access: yesEarly Medieval Europe, Volume 30, Issue 2, Page 159-184, May 2022., 2022
This article offers a fresh perspective on the life and works of the sixth‐century bishop Gregory of Tours by analysing Gregory’s magnum opus, the Histories, alongside a frequently overlooked aspect of his episcopal career: his restoration of the cathedral church of Tours and St Martin’s basilica following their devastation by fire in the time of his ...
John Merrington
wiley   +1 more source

A new method to estimate planktonic oxygen metabolism using high‐frequency sensor measurements in mesocosm experiments and considering daytime and nighttime respirations

open access: yesLimnology and Oceanography: Methods, Volume 19, Issue 5, Page 303-316, May 2021., 2021
Abstract Understanding how aquatic ecosystems respond to perturbations has emerged as a crucial way to predict the future of these ecosystems and to assess their capacity to produce oxygen and store atmospheric carbon. In this context, in situ mesocosm experiments are a useful approach for simulating disturbances and observing changes in planktonic ...
Tanguy Soulié   +4 more
wiley   +1 more source

136.30 / Instruction pastorale de l’humble évêque d’AIétopolis, à l’occasion de l’instruction pastorale de Jean George, humble évêque du Puy

open access: yes, 2023
Instruction pastorale de l’humble évêque d’AIétopolis, à l’occasion de l’instruction pastorale de Jean George, humble évêque du ...
Joana Roque Pesquer (16631319)
core   +1 more source

101.14 / Instruction pastorale de l’humble évêque d’Alétopolis, à l’occasion de l’instruction pastorale de Jean George, humble évêque du Puy

open access: yes, 2023
Instruction pastorale de l’humble évêque d’Alétopolis, à l’occasion de l’instruction pastorale de Jean George, humble évêque du ...
Joana Roque Pesquer (16631319)
core   +1 more source

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