Results 91 to 100 of about 4,791,418 (250)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
La présente contribution rend compte d’une recherche-intervention conduite à la demande d’un Centre de Ressources pour les Intervenants auprès des Auteurs de Violences Sexuelles (CRIAVS).
Dominique Broussal
doaj +1 more source
Version anglaise disponible dans la Bibliothèque numérique du CRDI: Working together to strengthen skills in individuals : IDRC's strategic evaluation of capacity development, phase
CRDI. Section de l'évaluation
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Version anglaise disponible dans la Bibliothèque numérique du CRDI: Working together to strengthen skills in organizations : IDRC's strategic evaluation of capacity development, phase
CRDI. Section de l'évaluation
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Lundi 13 mai 2019. ÉVALUATION GÉNÉRALE. Effets de l'ÉVALUATION #2
Journée d'études "Évaluation générale. Effets de l’évaluation # 2" Lundi 13 mai, 9h30-18h Université Paris 8, Salle des thèses Espace Deleuze (Bât. A 1er étage) Deuxième journée d'études autour du projet "Évaluation générale.
Nancy Murzilli
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Contexte : Suite à un traumatisme crânio-cérébral ou une lésion hémisphérique droite, de nombreux patients présentent des difficultés à comprendre le langage non littéral.
Natacha Cordonier +2 more
doaj +1 more source

