Results 101 to 110 of about 71,600,009 (285)

From Evaluation to Improvement: A Chief Justice’s Perspective

open access: yesOñati Socio-Legal Series, 2014
At the Supreme Court of Victoria, Australia, concepts of judicial performance and evaluation are relatively new. Responding to modern expectations for increased judicial accountability for their performance, Victorian judges have engaged a number of ...
Marilyn Warren
doaj   +2 more sources

Usos e Impacto de la Evaluación de la Docencia en la Universidad Autónoma del Estado de Hidalgo: Resultados de la Meta-evaluación

open access: yesRevista Iberoamericana de Evaluación Educativa, 2016
En el presente trabajo, se discute el impacto de los organismos internacionales en la generación de programas institucionales para favorecer la evaluación de la educación superior en México.
Leticia Elizalde Lora   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

¿Puede la Evaluación Docente Institucional Convertirse en Estrategia de Aprendizaje Profesional?

open access: yesRevista Iberoamericana de Evaluación Educativa, 2016
La evaluación de desempeño docente ha sido abordada más a nivel nacional que a nivel de las instituciones escolares. Los focos de análisis sobre el tema han estado en su orientación (calificación versus formación) y en la vinculación e incidencia de sus ...
Francisco Álvarez
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Évaluation d’un programme national de maternelle en milieux défavorisés

open access: yesCanadian Journal of Education, 2005
Cette étude examine le rendement scolaire et l’adaptation sociale de 10 369 élèves inscrits à un programme de maternelle à plein temps ou à demi‐temps. Les résultats scolaires des élèves issus de milieux économiquement faibles sont comparés à la fin de ...
Pierre Lapointe   +2 more
doaj   +2 more sources

Estudio del desempeño preclínico y clínico de una amalgama dental comercial Preclinical and clinical evaluation of a commercial dental amalgam

open access: yesRevista Facultad de Odontología Universidad de Antioquia, 2010
INTRODUCCIÓN: la amalgama de plata es un material restaurador para uso en dientes posteriores. El propósito de este estudio fue observar las características de trabajo de la amalgama dental Nu Alloy dp® en dientes de ivorina y, posteriormente, evaluar ...
Carlos Arturo Gómez Tabares   +1 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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