Results 111 to 120 of about 71,600,009 (285)

La Technique Delphi : une technique utile /

open access: yes, 1982
Bibliogr.: p.
Université Laval. Département de mesure et évaluation   +1 more
core  

1- Méthodologie générale - Recherche-évaluation Animation de la Vie Sociale

open access: yes
Ce jeu de données concerne la méthodologie générale du projet de recherche-évaluation sur l'animation de la vie sociale. Il comprend notamment le chapitre Méthodologie du rapport détaillé qui décrit l'ensemble du processus méthodologique et ses ...
LUCAS, Héloïse
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

2 - Focus groups - Recherche-évaluation Animation de la Vie Sociale

open access: yes
Cet ensemble de données concerne l'organisation d'une série de 7 focus groups : 4 focus group conduit avec 34 directions de centres sociaux ou espaces de vie sociale, et 3 focus group conduits avec 15 habitants fréquentant ces structures.
REVILLARD, Anne, LUCAS, Héloïse
core   +1 more source

Formula over Function? From Algorithms to Values in Judicial Evaluation

open access: yesOñati Socio-Legal Series, 2014
This paper discusses the forms and effects of the ‘invasion’ of the ‘temples of the law’ by new economic and managerial forms of performance evaluation.
Francesco Contini   +2 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

LE PEAGE URBAIN : UNE SOURCE DE FINANCEMENT ACCEPTABLE ? AVEC UNE APPLICATION AU CAS DE L’AGGLOMERATION STRASBOURGEOISE [PDF]

open access: yes
Après avoir brièvement rappelé les raisons par lesquelles la théorie économique justifie traditionnellement le recours au péage urbain, l’article examine les principaux éléments qui expliquent les résistances des agents économiques, afin d’en comprendre ...
Damien Broussolle
core  

Evaluation de la performance et de l'impact de la veille

open access: yes, 2015
A. Roulet   +2 more
semanticscholar   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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