Results 141 to 150 of about 71,600,009 (285)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
¿Qué Estamos Haciendo en Cuba en Evaluación Educativa?
Revista Iberoamericana de Evaluación Educativa, 2016 Este trabajo explica las acciones que hemos venido realizando en Cuba en materia de Evaluación Educativa. Primeramente, describimos los resultados de los Operativos Nacionales para la evaluación del rendimiento de los estudiantes.
Paul Torres
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Constatations en bref de l'examen externe des Partenariats canadiens
, 2010 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Findings brief : external review of the Canadian Partnerships ProgramCe texte présente les principales constatations du rapport intitulé Canadian Partnerships (CP) Program External ...
CRDI. Section de l'évaluation
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Revista Iberoamericana de Evaluación Educativa, 2016 Frente a la ausencia de un sistema de evaluación del desempeño docente en España, en los últimos años todas las Comunidades Autónomas han desarrollado propuestas de evaluación de los directores/as escolares al final de su mandato.
F. Javier Murillo Torrecilla +1 more
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Évaluation de la performance de remboursement dans les institutions de micro-finance au Bénin
, 2002 A. Honlonkou
semanticscholar +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Constatations en bref de l'examen externe du programme Pauvreté urbaine et environnement
, 2009 Version anglaise disponible dans la Bibliothèque numérique du CRDI: Findings brief : external review of the Urban Poverty and Environment ProgramCe texte présente les principales constatations du rapport intitulé Final Report to IDRC: Urban Poverty and
CRDI. Section de l'évaluation
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