Results 81 to 90 of about 189,704 (240)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Usos e Impacto de la Evaluación de la Docencia en la Universidad Autónoma del Estado de Hidalgo: Resultados de la Meta-evaluación

open access: yesRevista Iberoamericana de Evaluación Educativa, 2016
En el presente trabajo, se discute el impacto de los organismos internacionales en la generación de programas institucionales para favorecer la evaluación de la educación superior en México.
Leticia Elizalde Lora   +2 more
doaj  

A Monthly Indicator of the French Business Climate [PDF]

open access: yes
In France, the business tendency surveys conducted in all the important sectors of the economy are key components in diagnosing the economic outlook.
C. MINODIER, L. CLAVEL
core  

DIGITAL: multidisciplinary and multidimensional in the classrooms [PDF]

open access: yes, 2018
In this paper our aim is to analyse and present some pedagogical paths that prefigure and guide the teaching-learning devices developed "around" the digital tools.
Nobre, Ana
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

From Evaluation to Improvement: A Chief Justice’s Perspective

open access: yesOñati Socio-Legal Series, 2014
At the Supreme Court of Victoria, Australia, concepts of judicial performance and evaluation are relatively new. Responding to modern expectations for increased judicial accountability for their performance, Victorian judges have engaged a number of ...
Marilyn Warren
doaj   +2 more sources

Recommendations of the Stiglitz-Sen-Fitoussi Report: A few illustrations [PDF]

open access: yes
In September 2009 the Stiglitz-Sen-Fitoussi Commission submitted its report on the measurement of economic performance and social progress. The report is based on a large body of applied research work conducted in recent years in various fields of the ...
D. BLANCHET, M. CLERC, M. GAINI
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

L'intensité nodale, une évaluation de la performance de l'intermodalité dans les pôles d'échanges

open access: yes, 2011
National audienceL'aménagement de pôles d'échanges vise à faciliter les pratiques intermodales et à limiter les contraintes liées à la rupture de charge.
Richer, Cyprien, Vuidel, Gilles
core   +1 more source

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