Results 51 to 60 of about 8,743,550 (229)

Une analyse automatisée des modalités d'évaluation dans les MOOC

open access: yesInternational Journal of E-learning and Distance Education, 2018
Nous nous penchons sur les modalités d’évaluation d’une centaine de MOOC de la plate-forme France Université Numérique pour chercher à appréhender dans quelle mesure celles-ci pourraient contribuer à expliquer les faibles taux de certification qui y ...
Matthieu Cisel
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Evaluation of an Anti‐Bullying Program: Student Reports of Knowledge and Confidence to Manage Bullying

open access: yesCanadian Journal of Education, 2005
This research evaluates the effectiveness of an anti‐bullying program, Project Ploughshares Puppets for Peace (Woodfine, Lubimiv, & Langlois, 1995). Students in grades 3 and 4 (N = 129, 69 boys, 60 girls) from two public elementary schools completed a ...
Tanya Beran, Bonnie Shapiro
doaj   +2 more sources

Mixed Methods Findings of a Psychological First Aid Digital Peer Learning Program for Child-Supporting Professionals

open access: yesInternational Journal of First Aid Education
Background: The need to provide children affected by the armed conflict between Russia and Ukraine with mental health and psychosocial support (MHPSS) services outweighs available support.
Charlotte Njua Mbuh   +10 more
doaj   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation par les pairs : entre pratiques, expérimentations et controverses

open access: yes, 2016
Comment juger objectivement un article scientifique ?  L'objectivité du jugement par les pairs est-elle davantage garantie par l'anonymat des auteurs et/ou des reviewers ?
Pierre Naegelen
core  

Deregulating Naloxone to Combat Opioid-Related Overdoses in British Columbia

open access: yesHealth Reform Observer - Observatoire des Réformes de Santé, 2019
British Columbia fully unscheduled the opioid overdose-reversing drug known as naloxone on 21 September 2016 in an attempt to reduce opioid overdose-related mortality. Having a large population of injectable drug users, the move represents just one harm
Kody Crowell
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy