Results 61 to 70 of about 1,819,216 (267)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Psychology and Aging (2003-2012): productividad y rasgos desde los artículos originales

Revista Colombiana de Ciencias Sociales, 2014
El presente artículo realiza un análisis bibliométrico de la revista Psychology and Aging en el intervalo temporal 2003-2012. Esta revista es relevante en el área de la Gerontología y de la Psicología del desarrollo.
Manuel Martí-Vilar, Laura Estellés Asensi   +1 more
doaj  

Comparação do perfil dos pacientes que internaram na UTI do HU/UFSC e foram a óbito com o daqueles que receberam alta hospitalar. [PDF]

, 2005
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Cardoso, Hugo Alfredo Koerich Vieira
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Ãndice de massa corporal, obstrução aérea, dispneia e capacidade de exercício na Doença Pulmonar Obstrutiva Crónica (DPOC) â o índice BODE

Revista Portuguesa de Pneumologia, 2004
RESUMO: O estudo foi realizado entre 1997 e 2002 em 3 países (EUA, Espanha e Venezuela) num primeiro grupo de 207 doentes com DPOC, e em que existiu uma mortalidade de 12%.Dos vários parâmetros analisados e comparados entre sobreviventes e mortes, os que apresentaram maior valor preditivo de mortalidade foram: índice de massa corporal (B de BMI), o
B. Celli, C. Cote, J. Marin, C. Casanova, M. Oca, R. Mendez, V. Plata, H. Cabral   +7 more
openaire   +1 more source

Indices de la REVISTA COMPLUTENSE DE HISTORIA DE AMÉRICA. [PDF]

Sin ...
Índices, ÍNDICES
core   +1 more source

Monitorización de la actividad de la artritis reumatoide en la práctica clínica [PDF]

, 2017
La artritis reumatoide (AR) es una enfermedad inflamatoria crónica, que se caracteriza por una poliartritis, con tendencia a la cronicidad y evolución hacia la deformación y destrucción articular. Las estrategias actuales de manejo farmacológico de la
Sánchez López, Sergio
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Método para avaliar desenvolvimento sustentável: técnicas para escolha e ponderação de aspectos e dimensões Method to evaluate sustainable development: techniques for choice and balance of aspects and dimensions

Production, 2008
Materializar o conceito desenvolvimento sustentável é um problema complexo, pois as bases conceituais sobre as questões envolvidas não estão consolidadas.
Osmar Siena
doaj   +1 more source