Results 61 to 70 of about 109 (108)

Interface Controlled Electric Field Swing Adsorption

Advanced Science, EarlyView.
Swing adsorption of Ar, N2, and CO2 under moderate electric fields and elevated pressures at room temperature is investigated. Multiple charged conductor‐insulator interfaces enable a selective adsorption behavior of the three gases while CO2 shows a 10 fold increase in the effect over Ar and N2.
Silvio Heinschke, Jörg J. Schneider
wiley   +1 more source

Unveiling the Fundamental Principles of Reconfigurable Resistance States in Silver/Poly(Ethylene Glycol) Nanofluids

Advanced Science, EarlyView.
The electrophoretic reorganization of Ag nanoparticles within a poly(ethylene glycol) leads to the formation of conductive bridges with reconfigurable resistance states. Diverse conduction characteristics of the bridge range between ohmic conduction, nonlinear tunneling, or space charge‐limited conduction, and high resistance states.
Daniil Nikitin, Kateryna Biliak, Mariia Protsak, Blessing Adejube, Suren Ali‐Ogly, Kateřina Škorvanková, Veronika Červenková, Ronaldo Katuta, Marco Tosca, Jan Hanuš, Zulfiya Černochová, Peter Černoch, Petr Štěpánek, Oleksandr Boiko, Paulina Szymoniak, Andreas Schönhals, Franz Faupel, Hynek Biederman, Alexander Vahl, Andrei Choukourov   +19 more
wiley   +1 more source

Molecular Creep Induced Fatigue Rupture of Fibrin Clots

Advanced Science, EarlyView.
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu, Zichang Jia, Binchao Liu, Jizhe Hou, Rui Bao, Mingkun Wang   +5 more
wiley   +1 more source

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

Advanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu, Sang Soo Lee, Jiali Xiong, Shahin Ahmadi, Benjamin J. Bell, Mehmet F. Keles, Mark N. Wu   +6 more
wiley   +1 more source

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

Advanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini, Andrea Ciamarone, Sheila Dakhel Plaza, Tony Georgiev, Marta Mascellani, Emanuela Sabato, Giulio Vistoli, Ilaria Biancofiore, Nicholas Favalli, Emanuele Puca, Sebastian Oehler, Dario Neri, Samuele Cazzamalli   +12 more
wiley   +1 more source

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

Advanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo, Youngjun Kim, Rian Kang, Seho Lee, Dang Du Nguyen, Soomin Park, Dongjoon Lee, Jong Won Han, Inhee Mook‐Jung, Luke P. Lee, Jong‐Chan Park, Inki Kim   +11 more
wiley   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Quantum Kernel Learning for Small Dataset Modeling in Semiconductor Fabrication: Application to Ohmic Contact

Advanced Science, EarlyView.
A quantum kernel‐aligned regressor (QKAR) is developed for modeling Ohmic contact formation in GaN HEMT fabrication. Leveraging experimental data and a Pauli‐Z feature map enhanced with a quantum kernel alignment (QKA) layer, the model achieves superior predictive performance over classical methods.
Zeheng Wang, Fangzhou Wang, Liang Li, Zirui Wang, Timothy van der Laan, Ross C. C. Leon, Jing‐Kai Huang, Muhammad Usman   +7 more
wiley   +1 more source

Boron Difluoride Formazanate Dye With Donor Planarization Engineering for 1060 nm Laser Activated Photothermal Theranostics

Advanced Science, EarlyView.
The donor engineering strategy enhances the planarity of the π‐conjugated molecular framework, thereby promoting stronger intramolecular charge transfer (ICT). This structural refinement in FBDFDPA leads to a pronounced bathochromic shift in absorption from the NIR‐I to the NIR‐II region, enabling effective photothermal therapy (PTT) for tumors within ...
Kang Xu, Mengchen Luo, Weili Wang, Tian Zhang, Yang Chen, Jinjun Shao, Peng Chen, Xiaochen Dong, Yu Cai   +8 more
wiley   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source