Results 181 to 190 of about 6,308,624 (199)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Helminthological Survey of the European Brown Hare (Lepus europaeus) in Türkiye, with A Note on Haplotype and Network Analyses of Dicrocoelium dendriticum and Passalurus ambiguus. [PDF]

Acta Parasitol
Kalkan K, Erol U, Sahin OF, Sakar HF, Altay K.   +4 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Effects of vitamin D supplementation combined with resistance exercise on body composition and metabolic variables in older women: a randomized clinical trial. [PDF]

Clinics (Sao Paulo)
Queiroz IPDS, Alonso AC, da Silva VC, Machado-Lima A, Pipa PLAB, Soares-Junior JM, Baracat EC, Greve JMD, Bastos MF, Brech GC.   +9 more
europepmc   +1 more source

Treatment Outcome of Surgical Protocols for Peri-Implantitis: A Retrospective Cohort Study in a Specialised University Centre. [PDF]

J Clin Periodontol
Zhou W, Ramanauskaite A, Raabe C, Cafferata EA, Lingwal N, Schwarz F.   +5 more
europepmc   +1 more source

New deep-sea Amphipoda from the Clarion-Clipperton Zone: 24 new species described under the Sustainable Seabed Knowledge Initiative: One Thousand Reasons campaign. [PDF]

Zookeys
Jażdżewska AM, Horton T.
europepmc   +1 more source

Preterm Birth Increases Susceptibility to Hyperglycemia-Induced Kidney Injury With Sex-Specific Differences in Structural and Molecular Responses. [PDF]

Endocrinol Diabetes Metab
Dailey RK, Cwiek A, Hamil LC, Timberline S, Kameshwar AKS, Suzuki M, Isaac J, deRonde K, Conaway M, Bennett KM, Baldelomar EJ, Hoch MR, Reidy KJ, Charlton JR.   +13 more
europepmc   +1 more source

The dynamics of centromere assembly and disassembly during quiescence. [PDF]

J Cell Biol
Marescal O, Su KC, Moodie B, Taylor NJL, Cheeseman IM.   +4 more
europepmc   +1 more source