ИндуÑтриÑките водачи ги внеÑуваат VRML, Java и JavaScript во Web [PDF]
изваР...
информатика, МЕДИС -
core +1 more source
The Role of Exhaled Nitric Oxide in Childhood Asthma Management [PDF]
ÐÑтмата претÑтавува хронична инфламаторна болеÑÑ‚ на дишните патишта која Ñе карактеризира Ñо реверзибилна бронхообÑтрукција и појава на Ñимп
Jovkovska-Kaeva, Biserka +1 more
core +2 more sources
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
SurfWatch: "Заштитете ги вашите деца на Интернет " [PDF]
изваР...
информатика, МЕДИС -
core +1 more source
Screening for Diabetes Type 2 in Primary Health Care [PDF]
Вовед. Инцидената на Ð´Ð¸Ñ˜Ð°Ð±ÐµÑ‚ÐµÑ Ñ‚Ð¸Ð¿ 2 е во пораÑÑ‚. Во делот на раното откривање потребно е да Ñе најде интервенција која најдобро ќе ја препоР...
Iliev, Darko +2 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Letter: Changes in Blood Lactates during Ergometric Testing on Professional Football Players during One Half Season Competitions (Maced Med Electr J. 2015 Oct 02; 2015;50012. http://dx.doi.org/10.3889/mmej.2015.50012) [PDF]
ПоднеÑени Ñе забелешки од ИнÑтитутот за физиологија при МедицинÑкиот факултет во Скопје за автентичноÑта, плагијаризмот и другите етички Ð¾Ñ ...
Spiroski, Mirko
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

