Results 91 to 92 of about 92 (92)
Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Diaryl hydroxylamines have emerged as promising scaffolds for targeting the tryptophan‐catabolizing enzymes indoleamine 2,3‐dioxygenase 1 (IDO1) and tryptophan 2,3‐dioxygenase (TDO), key drivers of tumor immune escape. Building on the reported dual IDO1/TDO inhibitory activity of O‐((3,5‐difluorophenyl)(phenyl)methyl)hydroxylamine, a series of diaryl ...
Angeliki S. Foscolos +8 more
wiley +1 more source
Synthesis, Structure, and Thin Film Optical Properties of a Chiral Benzothiazole‐Derived Squaraine
ChemPhysChem, Volume 27, Issue 7, 14 April 2026.Solution‐processed thin films can be sensitive to the choice of solvent and thermal annealing, which we explore for a chiral benzothiazole squaraine. We observe peculiarly shaped excitonic circular dichroism in uniaxially anisotropic thin films, in which the presumed Davydov bands are spatially distributed exclusively into in‐plane (UDC) and out‐of ...
Marvin F. Schumacher +4 more
wiley +1 more source