Results 61 to 70 of about 8,592,770 (203)
Genetic and Transgenic Reagents for Drosophila simulans, D. mauritiana, D. yakuba, D. santomea, and D. virilis
G3: Genes, Genomes, Genetics, 2017 Species of the Drosophila melanogaster species subgroup, including the species D. simulans, D. mauritiana, D. yakuba, and D. santomea, have long served as model systems for studying evolution.David L. Stern, Justin Crocker, Yun Ding, Nicolas Frankel, Gretchen Kappes, Elizabeth Kim, Ryan Kuzmickas, Andrew Lemire, Joshua D. Mast, Serge Picard +9 moredoaj +1 more sourceEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourcePhosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia +3 morewiley +1 more sourceCrosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada +8 morewiley +1 more sourceFunction‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang +9 morewiley +1 more sourceMultiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst +6 morewiley +1 more sourceThe newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...Dylan Casey, Zeqian Gao, Joan Boyeswiley +1 more sourceMeasurement of the CP asymmetry in B − → D s − D 0 and B − → D − D 0 decays
Journal of High Energy Physics, 2018 The CP asymmetry in B − → D s − D 0 and B − → D − D 0 decays is measured using LHCb data corresponding to an integrated luminosity of 3.0 fb−1, collected in pp collisions at centre-of-mass energies of 7 and 8 TeV. The results are ACPB−→Ds−D0=−0.4±0.5±0.5%The LHCb collaboration, R. Aaij, B. Adeva, M. Adinolfi, Z. Ajaltouni, S. Akar, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, A. Alfonso Albero, S. Ali, G. Alkhazov, P. Alvarez Cartelle, A. A. Alves, S. Amato, S. Amerio, Y. Amhis, L. An, L. Anderlini, G. Andreassi, M. Andreotti, J. E. Andrews, R. B. Appleby, F. Archilli, P. d’Argent, J. Arnau Romeu, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, G. Auriemma, S. Bachmann, J. J. Back, S. Baker, V. Balagura, W. Baldini, A. Baranov, R. J. Barlow, S. Barsuk, W. Barter, F. Baryshnikov, V. Batozskaya, V. Battista, A. Bay, J. Beddow, F. Bedeschi, I. Bediaga, A. Beiter, L. J. Bel, N. Beliy, V. Bellee, N. Belloli, K. Belous, I. Belyaev, E. Ben-Haim, G. Bencivenni, S. Benson, S. Beranek, A. Berezhnoy, R. Bernet, D. Berninghoff, E. Bertholet, A. Bertolin, C. Betancourt, F. Betti, M. O. Bettler, M. van Beuzekom, Ia. Bezshyiko, S. Bifani, P. Billoir, A. Birnkraut, A. Bizzeti, M. Bjørn, T. Blake, F. Blanc, S. Blusk, V. Bocci, O. Boente Garcia, T. Boettcher, A. Bondar, N. Bondar, S. Borghi, M. Borisyak, M. Borsato, F. Bossu, M. Boubdir, T. J. V. Bowcock, E. Bowen, C. Bozzi, S. Braun, M. Brodski, J. Brodzicka, D. Brundu, E. Buchanan, C. Burr, A. Bursche, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, R. Calladine, M. Calvi, M. Calvo Gomez, A. Camboni, P. Campana, D. H. Campora Perez, L. Capriotti, A. Carbone, G. Carboni, R. Cardinale, A. Cardini, P. Carniti, L. Carson, K. Carvalho Akiba, G. Casse, L. Cassina, M. Cattaneo, G. Cavallero, R. Cenci, D. Chamont, M. G. Chapman, M. Charles, Ph. Charpentier, G. Chatzikonstantinidis, M. Chefdeville, S. Chen, S.-G. Chitic, V. Chobanova, M. Chrzaszcz, A. Chubykin, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, V. Coco, J. Cogan, E. Cogneras, V. Cogoni, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, A. Contu, G. Coombs, S. Coquereau, G. Corti, M. Corvo, C. M. Costa Sobral, B. Couturier, G. A. Cowan, D. C. Craik, A. Crocombe, M. Cruz Torres, R. Currie, C. D’Ambrosio, F. Da Cunha Marinho, C. L. Da Silva, E. Dall’Occo, J. Dalseno, A. Danilina, A. Davis, O. De Aguiar Francisco, K. De Bruyn, S. De Capua, M. De Cian, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, C. T. Dean, D. Decamp, L. Del Buono, B. Delaney, H.-P. Dembinski, M. Demmer, A. Dendek, D. Derkach, O. Deschamps, F. Dettori, B. Dey, A. Di Canto, P. Di Nezza, S. Didenko, H. Dijkstra, F. Dordei, M. Dorigo, A. Dosil Suárez, L. Douglas, A. Dovbnya, K. Dreimanis, L. Dufour, G. Dujany, P. Durante, J. M. Durham, D. Dutta, R. Dzhelyadin, M. Dziewiecki, A. Dziurda, A. Dzyuba, S. Easo, U. Egede, V. Egorychev, S. Eidelman, S. Eisenhardt, U. Eitschberger, R. Ekelhof, L. Eklund, S. Ely, A. Ene, S. Escher, S. Esen, H. M. Evans, T. Evans, A. Falabella, N. Farley, S. Farry, D. Fazzini, L. Federici, G. Fernandez, P. Fernandez Declara, A. Fernandez Prieto, F. Ferrari, L. Ferreira Lopes, F. Ferreira Rodrigues, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, M. Firlej, C. Fitzpatrick, T. Fiutowski, F. Fleuret, M. Fontana, F. Fontanelli, R. Forty, V. Franco Lima, M. Frank, C. Frei, J. Fu, W. Funk, C. Färber, E. Gabriel, A. Gallas Torreira, D. Galli, S. Gallorini, S. Gambetta, M. Gandelman, P. Gandini, Y. Gao, L. M. Garcia Martin, B. Garcia Plana, J. García Pardiñas, J. Garra Tico, L. Garrido, D. Gascon, C. Gaspar, L. Gavardi, G. Gazzoni, D. Gerick, E. Gersabeck, M. Gersabeck, T. Gershon, Ph. Ghez, S. Gianí, V. Gibson, O. G. Girard, L. Giubega, K. Gizdov, V. V. Gligorov, D. Golubkov, A. Golutvin, A. Gomes, I. V. Gorelov, C. Gotti, E. Govorkova, J. P. Grabowski, R. Graciani Diaz, L. A. Granado Cardoso, E. Graugés, E. Graverini, G. Graziani, A. Grecu, R. Greim, P. Griffith, L. Grillo, L. Gruber, B. R. Gruberg Cazon, O. Grünberg, E. Gushchin, Yu. Guz, T. Gys, C. Göbel, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, S. C. Haines, B. Hamilton, X. Han, T. H. Hancock, S. Hansmann-Menzemer, N. Harnew, S. T. Harnew, C. Hasse, M. Hatch, J. He, M. Hecker, K. Heinicke, A. Heister, K. Hennessy, L. Henry, E. van Herwijnen, M. Heß, A. Hicheur, D. Hill, P. H. Hopchev, W. Hu, W. Huang, Z. C. Huard, W. Hulsbergen, T. Humair, M. Hushchyn, D. Hutchcroft, P. Ibis, M. Idzik, P. Ilten, K. Ivshin, R. Jacobsson, J. Jalocha, E. Jans, A. Jawahery, F. Jiang, M. John, D. Johnson, C. R. Jones, C. Joram, B. Jost, N. Jurik, S. Kandybei, M. Karacson, J. M. Kariuki, S. Karodia, N. Kazeev, M. Kecke, F. Keizer, M. Kelsey, M. Kenzie, T. Ketel, E. Khairullin, B. Khanji, C. Khurewathanakul, K. E. Kim, T. Kirn, S. Klaver, K. Klimaszewski, T. Klimkovich, S. Koliiev, M. Kolpin, R. Kopecna, P. Koppenburg, S. Kotriakhova, M. Kozeiha, L. Kravchuk, M. Kreps, F. Kress, P. Krokovny, W. Krupa, W. Krzemien, W. Kucewicz, M. Kucharczyk, V. Kudryavtsev, A. K. Kuonen, T. Kvaratskheliya, D. Lacarrere, G. Lafferty, A. Lai, G. Lanfranchi, C. Langenbruch, T. Latham, C. Lazzeroni, R. Le Gac, A. Leflat, J. Lefrançois, R. Lefèvre, F. Lemaitre, P. Lenisa, O. Leroy, T. Lesiak, B. Leverington, P.-R. Li, T. Li, Z. Li, X. Liang, T. Likhomanenko, R. Lindner, F. Lionetto, V. Lisovskyi, X. Liu, D. Loh, A. Loi, I. Longstaff, J. H. Lopes, D. Lucchesi, M. Lucio Martinez, A. Lupato, E. Luppi, O. Lupton, A. Lusiani, X. Lyu, F. Machefert, F. Maciuc, V. Macko, P. Mackowiak, S. Maddrell-Mander, O. Maev, K. Maguire, D. Maisuzenko, M. W. Majewski, S. Malde, B. Malecki, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, D. Marangotto, J. Maratas, J. F. Marchand, U. Marconi, C. Marin Benito, M. Marinangeli, P. Marino, J. Marks, G. Martellotti, M. Martin, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, Z. Mathe, C. Matteuzzi, A. Mauri, E. Maurice, B. Maurin, A. Mazurov, M. McCann, A. McNab, R. McNulty, J. V. Mead, B. Meadows, C. Meaux, F. Meier, N. Meinert, D. Melnychuk, M. Merk, A. Merli, E. Michielin, D. A. Milanes, E. Millard, M.-N. Minard, L. Minzoni, D. S. Mitzel, A. Mogini, J. Molina Rodriguez, T. Mombächer, I. A. Monroy, S. Monteil, M. Morandin, G. Morello, M. J. Morello, O. Morgunova, J. Moron, A. B. Morris, R. Mountain, F. Muheim, M. Mulder, D. Müller, J. Müller, K. Müller, V. Müller, P. Naik, T. Nakada, R. Nandakumar, A. Nandi, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, M. Neuner, T. D. Nguyen, C. Nguyen-Mau, S. Nieswand, R. Niet, N. Nikitin, A. Nogay, D. P. O’Hanlon, A. Oblakowska-Mucha, V. Obraztsov, S. Ogilvy, R. Oldeman, C. J. G. Onderwater, A. Ossowska, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, P. R. Pais, A. Palano, M. Palutan, G. Panshin, A. Papanestis, M. Pappagallo, L. L. Pappalardo, W. Parker, C. Parkes, G. Passaleva, A. Pastore, M. Patel, C. Patrignani, A. Pearce, A. Pellegrino, G. Penso, M. Pepe Altarelli, S. Perazzini, D. Pereima, P. Perret, L. Pescatore, K. Petridis, A. Petrolini, A. Petrov, M. Petruzzo, B. Pietrzyk, G. Pietrzyk, M. Pikies, D. Pinci, F. Pisani, A. Pistone, A. Piucci, V. Placinta, S. Playfer, M. Plo Casasus, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, G. J. Pomery, S. Ponce, A. Popov, D. Popov, S. Poslavskii, C. Potterat, E. Price, J. Prisciandaro, C. Prouve, V. Pugatch, A. Puig Navarro, H. Pullen, G. Punzi, W. Qian, J. Qin, R. Quagliani, B. Quintana, B. Rachwal, J. H. Rademacker, M. Rama, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Ravonel Salzgeber, M. Reboud, F. Redi, S. Reichert, A. C. dos Reis, C. Remon Alepuz, V. Renaudin, S. Ricciardi, S. Richards, K. Rinnert, P. Robbe, A. Robert, A. B. Rodrigues, E. Rodrigues, J. A. Rodriguez Lopez, A. Rogozhnikov, S. Roiser, A. Rollings, V. Romanovskiy, A. Romero Vidal, M. Rotondo, M. S. Rudolph, T. Ruf, J. Ruiz Vidal, J. J. Saborido Silva, N. Sagidova, B. Saitta, V. Salustino Guimaraes, C. Sanchez Mayordomo, B. Sanmartin Sedes, R. Santacesaria, C. Santamarina Rios, M. Santimaria, E. Santovetti, G. Sarpis, A. Sarti, C. Satriano, A. Satta, D. Savrina, S. Schael, M. Schellenberg, M. Schiller, H. Schindler, M. Schmelling, T. Schmelzer, B. Schmidt, O. Schneider, A. Schopper, H. F. Schreiner, M. Schubiger, M. H. Schune, R. Schwemmer, B. Sciascia, A. Sciubba, A. Semennikov, E. S. Sepulveda, A. Sergi, N. Serra, J. Serrano, L. Sestini, P. Seyfert, M. Shapkin, Y. Shcheglov, T. Shears, L. Shekhtman, V. Shevchenko, B. G. Siddi, R. Silva Coutinho, L. Silva de Oliveira, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, I. T. Smith, M. Smith, l. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, B. Souza De Paula, B. Spaan, P. Spradlin, F. Stagni, M. Stahl, S. Stahl, P. Stefko, S. Stefkova, O. Steinkamp, S. Stemmle, O. Stenyakin, M. Stepanova, H. Stevens, S. Stone, B. Storaci, S. Stracka, M. E. Stramaglia, M. Straticiuc, U. Straumann, S. Strokov, J. Sun, L. Sun, K. Swientek, V. Syropoulos, T. Szumlak, M. Szymanski, S. T’Jampens, Z. Tang, A. Tayduganov, T. Tekampe, G. Tellarini, F. Teubert, E. Thomas, J. van Tilburg, M. J. Tilley, V. Tisserand, M. Tobin, S. Tolk, L. Tomassetti, D. Tonelli, R. Tourinho Jadallah Aoude, E. Tournefier, M. Traill, M. T. Tran, M. Tresch, A. Trisovic, A. Tsaregorodtsev, A. Tully, N. Tuning, A. Ukleja, A. Usachov, A. Ustyuzhanin, U. Uwer, C. Vacca, A. Vagner, V. Vagnoni, A. Valassi, S. Valat, G. Valenti, R. Vazquez Gomez, P. Vazquez Regueiro, S. Vecchi, M. van Veghel, J. J. Velthuis, M. Veltri, G. Veneziano, A. Venkateswaran, T. A. Verlage, M. Vernet, M. Vesterinen, J. V. Viana Barbosa, D. Vieira, M. Vieites Diaz, H. Viemann, X. Vilasis-Cardona, A. Vitkovskiy, M. Vitti, V. Volkov, A. Vollhardt, B. Voneki, A. Vorobyev, V. Vorobyev, C. Voß, J. A. de Vries, C. Vázquez Sierra, R. Waldi, J. Walsh, J. Wang, M. Wang, Y. Wang, Z. Wang, D. R. Ward, H. M. Wark, N. K. Watson, D. Websdale, A. Weiden, C. Weisser, M. Whitehead, J. Wicht, G. Wilkinson, M. Wilkinson, M. R. J. Williams, M. Williams, T. Williams, F. F. Wilson, J. Wimberley, M. Winn, J. Wishahi, W. Wislicki, M. Witek, G. Wormser, S. A. Wotton, K. Wyllie, D. Xiao, Y. Xie, A. Xu, M. Xu, Q. Xu, Z. Xu, Z. Xu, Z. Yang, Z. Yang, Y. Yao, H. Yin, J. Yu, X. Yuan, O. Yushchenko, K. A. Zarebski, M. Zavertyaev, L. Zhang, Y. Zhang, A. Zhelezov, Y. Zheng, X. Zhu, V. Zhukov, J. B. Zonneveld, S. Zucchelli +791 moredoaj +1 more source
