Results 151 to 160 of about 6,167,205 (249)

Evaluation of practices for the diagnosis and monitoring of cytomegalovirus infection in kidney transplant recipients in Brazil. [PDF]

J Bras Nefrol
Hatem NA, Keitel E, Santoro-Lopes G, Pierrotti LC, Pasqualotto AC.   +4 more
europepmc   +1 more source

ОÑврт на два Ñлучаја муковиÑцидоза (Fibrosis Cystica) кај новородено

, 2017
Two sucker babies with fibrosa cystic have been presented: in one of them the disease was severe with the lethal outcome, while the other baby could be successfully treated.
СпировÑки (Spirovski), Зоран (Zoran), Серафимов (Serafimov), Виктор (Viktor), Гордова-МуратовÑка (Gordova-Muratovska), ÐлекÑандра (Aleksandra)   +2 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Vitamin D status and type 2 diabetes incidence in Finnish adults-a longitudinal survey and register-based study using standardized serum 25-hydroxyvitamin D data. [PDF]

Eur J Nutr
Adebayo FA, Itkonen ST, Jääskeläinen T, Härkänen T, Cashman KD, Erkkola M, Lamberg-Allardt C.   +6 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

NMNAT1 Activates Autophagy to Delay D-Galactose-Induced Aging in Cochlear Hair Cells. [PDF]

Aging Cell
Wei Y, Yang W, Wu H, Kong M, Fan D, Zhang Y, Cheng N, Du J, Guo L, Li Y, Zhang Y, Dai Q, Cao W, Yang J, Fang Q.   +14 more
europepmc   +1 more source

За ликот на акад. Димитар ÐÑ€Ñов

, 2016
No abstract available.Ðема изваР...
СтолевÑки (Stolevski), Владо (Vlado)
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Заштита на информациÑки ÑиÑтеми

, 2016
ИзваР...
ДимитриевÑки, Томе
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source