Results 101 to 110 of about 6,426,241 (257)

Епидемиолошко-клиничка корелација кај заболени од вируÑен хепатит врз клинички материјал

, 2016
The epidemiologic-clinical correlation at 170 patients of hepatitis virosa (VH) indicated the following:It is intensify the sessional frequency of ill patients with the evident increase about Jun-August (10.58), and with the extreme top in the course of ...
Караџов (Karadzhov), Зоран (Zoran), СтолевÑки (Stolevski), Владо (Vlado), ГруневÑка (Grunevska), Бојана (Bojana)   +2 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Верификација на квалитативни методи Ñо теÑÑ‚ ленти за иÑпитување на дроги кои Ñе злоупотребуваат во урина

, 2018
The verification of the  qualitative method with test  devices for detection of eight drugs of abuse in urine  (amphetamines, methamphetamine,  barbiturates,  benzoylecgonine,  marijuana, 3,4-methylendioxy-methamphetamine, methadone, and opiates) was ...
ТошеÑка-ТрајковÑка (Tosheska-Trajkovska), Катерина (Katerina), ТопузовÑка (Topuzovska), Соња (Sonja), Лабудовиќ (Labudovik), Даница (Danica), ЦековÑка (Cekovska), Светлана (Svetlana), БогданÑка (Bogdanska), ЈаÑна (Jasna)   +4 more
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

ЗдравÑтвени ризици при изложеноÑÑ‚ на азбеÑÑ‚ во животната Ñредина - преглед на литературата и ÑоÑтојба во Rепублика Mакедонија

, 2017
International Agency for Research on Cancer (IARC) in 2009 classified all forms of asbestos as sure human carcinogen (Group 1) for lung cancer, mesothelioma of the pleura, and cancer of the larynx and ovary.
Минов (Minov), Јордан (Jordan), КараџинÑка БиÑлимовÑка (Karadzinska Bislimovska), Јованка (Jovanka), РиÑтовÑка (Ristovska), Гордана (Gordana)   +2 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Три Ñлучаи на Syndroma Willi Prader Labhardt во доенечка возраÑÑ‚

, 2017
Authors presented three cases of Willi Prader Labhardt Syndroma whose cardinal symptoms are: psychomotor retardation, proportional obesity, hypogenitalism, a small bifrontal circumference, and carp-like mouth.During the pregnancy, children's mothers felt
Гордова-МуратовÑка (Gordova-Muratovska), ÐлекÑандра (Aleksandra), Серафимов (Serafimov), Виктор (Viktor), СпировÑки, Зоран   +2 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source