Results 121 to 130 of about 8,492,114 (295)

Aligned Spins: Orbital Elements, Decaying Orbits, and Last Stable Circular Orbit to high post-Newtonian Orders

open access: yes, 2015
In this article the quasi-Keplerian parameterisation for the case that spins and orbital angular momentum in a compact binary system are aligned or anti-aligned with the orbital angular momentum vector is extended to 3PN point-mass, next-to-next-to ...
Bogdanović T   +11 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

B ¯ → D ¯ D $$ \overline{B}\to \overline{D}D $$ decays and the extraction of f d /f u at hadron colliders

open access: yesJournal of High Energy Physics
We perform a detailed model-independent phenomenological analysis of B ¯ → D ¯ D $$ \overline{B}\to \overline{D}D $$ decays. Employing an SU(3) F analysis including symmetry-breaking contributions together with a conservative power counting for various ...
Jonathan Davies   +2 more
doaj   +1 more source

Város és vonzáskörzete: gazdasági kapcsolatrendszer és növekedés : Vázlat a győri járműipari körzet regionális makromodelljének kidolgozásához = City and agglomeration : economic relations and growth [PDF]

open access: yes, 2014
Economic analysis of an area, exploring its macroeconomic relations using quantitative methods, can have a great importance on both national and regional levels. The authors’ long-term objective is to develop a regional macroeconomic model calibrated for
Koppány, Krisztián   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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