Optimal Adjuvant Therapy Selection for Chinese BRAF V600-Mutant Stage III Melanoma: A Multicenter Efficacy Comparison of Targeted Agents, Immunotherapy, and Combinatorial Strategies. [PDF]
Zhang R +17 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Sugar-Sweetened Beverages Consumption among Koreans: Differences across Age Groups and Beverage Types. [PDF]
Ganbat K, Kim BH, Song S.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Dual Cluster-Surface Click Chemistries on Silver Nanoclusters. [PDF]
Vega Verduga C +5 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
ШевÑенко, Ð. Ю.; ÐаÑионалÑнÑй авиаÑионнÑй ÑнивеÑÑиÑеÑ
openalex +1 more source
The Impact of Serum 25-Hydroxyvitamin D on Bone Mineral Density at Different Skeletal Sites: A Multivariate Analysis Based on a UK Cohort Study. [PDF]
Zeng H +7 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Triphenylmethyl Group as a Highly Diastereoselective <i>exo</i>,<i>endo</i>-Auxiliary in Double Diels-Alder Reactions with 2<i>H</i>-Pyran-2-ones. [PDF]
Krivec M +3 more
europepmc +1 more source

