Results 151 to 160 of about 9,273,634 (241)

Фрактури на долен вратен 'рбет, заден или преден приÑтап

, 2016
ИзваР...
Тодоров (Todorov), Илија (Ilija)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Long-Term Performance and Bulk-Isotope Effects in Methane Clumped-Isotope Measurements Using a 253 Ultra HR-IRMS. [PDF]

Rapid Commun Mass Spectrom
Zhang N, Gilbert A, Nakagawa M, Surma J, Meissner JGC, Mohn J, Bernasconi SM, Ueno Y, Yoshida N.   +8 more
europepmc   +1 more source

Епидемиолошко-клиничка корелација кај заболени од вируÑен хепатит врз клинички материјал

, 2016
The epidemiologic-clinical correlation at 170 patients of hepatitis virosa (VH) indicated the following:It is intensify the sessional frequency of ill patients with the evident increase about Jun-August (10.58), and with the extreme top in the course of ...
Караџов (Karadzhov), Зоран (Zoran), СтолевÑки (Stolevski), Владо (Vlado), ГруневÑка (Grunevska), Бојана (Bojana)   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A Glial Interplay Regulates Junctional Architecture at the Blood-Brain Barrier of Drosophila. [PDF]

Glia
Contreras EG, Naffin E, Collins-Ramírez M, Surina NV, Rothermel M, Salazar-Tirado J, Schirmeier S, Klämbt C.   +7 more
europepmc   +1 more source

PCI Mac го подигнува нивото на преформанÑи

, 2016
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информатика, МЕДИС -
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Содржина, декември, 1996, волумен 3, број 23

, 2016
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информатика, МЕДИС -
core