Results 71 to 80 of about 9,138,381 (257)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Intensification of systemic chemotherapy with in- clusion of high doses methotrexate (MTX) has contributed to the improvement of event-free survival in children with acute lymphoblastic leukemia (ALL). Despite this benefit, this agent might cause serious
ЕфтимијадоÑка (Eftimijadoska), Фани (Fani)
core
This study investigates the three-body decay process $$B^{+} \rightarrow D^{*+} D^{-} K^{+}$$ B + → D ∗ + D - K + , aiming to explore the possible origins of $$T^{*}_{\bar{c}\bar{s}0}(2870)^0$$ T c ¯ s ¯ 0 ∗ ( 2870 ) 0 and $$\chi _{c1}(3872)$$ χ c 1 ...
Zuo-Ming Ding, Qi Huang, Jun He
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
In this paper, a systematic investigation is conducted to explore the potential molecular states formed by heavy meson pairs $$D^{(*)}D^{(*)}$$ D ( ∗ ) D ( ∗ ) and $$D^{(*)}{\bar{D}}^{(*)}$$ D ( ∗ ) D ¯ ( ∗ ) with the complex scaling method, in the ...
Jia-Liang Lu +5 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Морбили во фаза на задолжителна вакцинација
The conclusion of the authors is that, beside the vaccination, measles are still present in our pathology.The most frequent and the hardest complications are respiratory ones as bronchopneumonia, pneumonia, bronchitis, bronchiolitis, stomatitis, and ...
Караџов (Karadzhov), Зоран (Zoran) +2 more
core
Species of the Drosophila melanogaster species subgroup, including the species D. simulans, D. mauritiana, D. yakuba, and D. santomea, have long served as model systems for studying evolution.
David L. Stern +9 more
doaj +1 more source

