Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. [PDF]
Mann JFE +22 more
europepmc +1 more source
Mapping implementation barriers and facilitators of a physical activity consultation in the Portuguese primary healthcare: a qualitative approach combining the Tailored Implementation for Chronic Diseases and Behaviour Change Wheel frameworks. [PDF]
Silva CS +7 more
europepmc +1 more source
Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung. [PDF]
Joy N +15 more
europepmc +1 more source
Modeling, Evaluation, and In Vivo Estimation of Muscle Cell Diameter With the Random Permeable Barrier Model: Correlation With Subject Characteristics and Isometric Torque. [PDF]
Froeling M +4 more
europepmc +1 more source
Apelin-13 confers Neuropeptide Y-mediated neuroprotection and preserves learning and allocentric memory in D-glutamic acid-induced excitotoxicity in rats. [PDF]
Oruc KY +11 more
europepmc +1 more source
Rotation reversal of chiral bacterial vortices.
Htet PH, Lauga E.
europepmc +1 more source

