Results 111 to 120 of about 5,658,429 (212)

Investigation of Optimal Parameters Setting for Negative Pressure Wound Therapy With Instillation and Dwell Time for Hard-To-Heal Wounds With Necrotic Tissue. [PDF]

Int Wound J
Ohura N, Sakisaka M, Nakayama D, Kinoshita M.   +3 more
europepmc   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

A 10-year retrospective study on the prevalence and biometric characteristics of high myopia in Chinese cataract surgery candidates. [PDF]

Sci Rep
Tan Y, Shao Y, Liu L, Pei Z, Peng M, Wu Y, Xu Y, Zhou X, Wang X.   +8 more
europepmc   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Clinical characteristics and survival outcomes of rectal cancer patients across different mrT3 substages determined by rectal MRI. [PDF]

Int J Colorectal Dis
Li G, Zhang X, Qiu X, Xu L, Lu J, Wu B, Xiao Y, Lin G.   +7 more
europepmc   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Bolt loosening evaluation method based on normalized screw root equivalent stress and loosening life curve. [PDF]

Sci Rep
Yang G, Zhao H, Yang L, Shao W, Xiao S, Zhu T, Yuan Y.   +6 more
europepmc   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Design, synthesis, and anti-urease evaluations of new sulfonamide-1,2,3-triazole-acetamide derivatives. [PDF]

Sci Rep
Varzaneh SB, Shokouhi Asl AS, Sayahi MH, Taherkhani AM, Talebi M, Dastyafteh N, Safapoor S, Emadi M, Alikhani M, Yazzaf R, Halimi M, Amanlou M, Larijani B, Mohammadi-Khanaposhtani M, Mahdavi M.   +14 more
europepmc   +1 more source

Дизморфофобија и еÑтетÑка хирургија

, 2015
Marija Miloshevska MijalkovsÐoa, Gjorgje Dzokic, Hristina Breshkovska, Ana Tomanovic Todorova   +3 more
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