Results 111 to 120 of about 6,055,275 (250)

ÐÑодвижение кÑеаÑивно-кÑлÑÑÑÑного пÑоÑÑÑанÑÑва ÑÑедÑÑвами ÑÐµÐºÐ»Ð°Ð¼Ñ Ð¸ PR (на пÑимеÑе ÐÐР«ÐУÐл)

, 2017
Алена Александровна Ливандовская
openalex   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

СовеÑÑенÑÑвование моÑиваÑии пеÑÑонала пÑÑем внедÑÐµÐ½Ð¸Ñ Ð¿ÑемиалÑной ÑиÑÑÐµÐ¼Ñ Ð¾Ð¿Ð»Ð°ÑÑ ÑÑÑда Ð´Ð»Ñ Ð¾ÑганизаÑии (на пÑимеÑе ÐÐ "61 ÐТРÐ")

, 2017
Елена Валерьевна Синякина
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Ðнализ влиÑÐ½Ð¸Ñ ÑезÑлÑÑаÑов деÑÑелÑноÑÑи доÑеÑÐ½Ð¸Ñ Ð¾ÑганизаÑий на показаÑели ÑинанÑовой оÑÑеÑноÑÑи Ñ Ð¾Ð»Ð´Ð¸Ð½Ð³Ð°

, 2017
Елизавета Вадимовна Попкова
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Evaluation of practices for the diagnosis and monitoring of cytomegalovirus infection in kidney transplant recipients in Brazil. [PDF]

J Bras Nefrol
Hatem NA, Keitel E, Santoro-Lopes G, Pierrotti LC, Pasqualotto AC.   +4 more
europepmc   +1 more source

ÐовÑÑÐ½Ñ Ð²Ð¿ÑÐ¾Ð²Ð°Ð´Ð¶ÐµÐ½Ð½Ñ Ð² педагогÑÑний пÑоÑÐµÑ Ð²Ð¸ÐºÐ»Ð°Ð´Ð°Ð½Ð½Ñ ÑадÑологÑÑ Ð½Ð° ÑÑеÑÑÐ¾Ð¼Ñ ÐºÑÑÑÑ Ð¼ÐµÐ´Ð¸Ñного ÑакÑлÑÑеÑÑ

, 2015
І. М. Леськів І. В. Жулкевич І. Й. Галайчук, Н. О. Загурська   +1 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Synthesis and characterization of poly [N-acryloyl-(D/L), (+/−)-phenylalanine-co-(D/L), (−/+)N-methacryloyloxyethyl-N′-2-hydroxybutyl(urea)] copolymers

Open Chemistry, 2014
Buruiana Emil, Murariu Mioara, Buruiana Tinca   +2 more
doaj   +1 more source