Results 151 to 160 of about 6,426,239 (248)

Prevalence, Disease Onset and Clinical Outcome in Arginase 1 Deficiency: Cross-Border Surveillance in Germany, Austria, and Switzerland. [PDF]

J Inherit Metab Dis
Scharre S, Hess AL, Gleich F, Garbade SF, Feyh P, Karall D, Baghdasaryan A, Huemer M, Hennermann JB, Hahn A, Lindner M, Gramer G, Luecke T, Kleinelanghorst N, Haeberle J, Lotz-Havla AS, Hoffmann GF, Okun JG, Muetze U, Kölker S.   +19 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

ЕФЕКТИ ÐÐ CYP3A4 ГЕÐЕТСКИ ПОЛИМОРФИЗÐÐœ ВРЗ ПОСТОПЕРÐТИВÐÐТРПОТРОШУВÐЧКРÐРФЕÐТÐÐИЛ ПРИ ТРЕТМÐÐ ÐРПОСТОПЕРÐТИВÐÐТРБОЛКÐ

, 2017
Минималната ефективна концентрација на опиоиден аналгетик може значајно да Ñе разликува меѓу пациентите.
СпировÑка, Татјана, Карталов, Ðндријан, Ðојков, Јордан, ТрајковÑки, Ѓорѓи, МатевÑка-ГешковÑка, Ðадица, ÐамбазовÑка-ТрајковÑка, Вања, ДимовÑки, ÐлекÑандар, Сељмани, Реџеп, КузмановÑка, Биљана   +8 more
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Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity-Dependent in Adult Rats. [PDF]

Glia
Mountadem S, Hilal ML, Pommier D, Arnouil D, Langlais VC, Simon V, Amadio A, Miegebielle M, Marais S, Joséphine C, Cannich A, Varilh M, Bourel J, Cota D, Marsicano G, Bemelmans AP, Ciofi P, Oliet SHR, Panatier A.   +18 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Современи трендови за развој на информативни ÑиÑтеми

, 2016
ИзваР...
Грнаров, ÐкÑенти
core  

Synthesis and characterization of poly [N-acryloyl-(D/L), (+/−)-phenylalanine-co-(D/L), (−/+)N-methacryloyloxyethyl-N′-2-hydroxybutyl(urea)] copolymers

Open Chemistry, 2014
Buruiana Emil, Murariu Mioara, Buruiana Tinca   +2 more
doaj   +1 more source

Activation of Intestinal Type 3 Innate Lymphoid Cells and Regulatory T Cells Through Free Fatty Acid Receptor 2 Ameliorates Type 1 Diabetes in Mice. [PDF]

Diabetes
Koprivica I, Jonić N, Dimitrijević M, Jevtić B, Mićanović D, Stegnjaić G, Lazarević M, Stanisavljević S, Pilipović I, Radulović N, Saksida T, Mišić D, Zdravković V, Fraser G, Miljković Đ, Stojanović I.   +15 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

ЛапароÑкопÑка апендектомија кај деца во Република Македонија

, 2017
Acute appendicitis is very common acute surgical condition in childhood that  requires quick and safe treatment with least possible complications.
Симеонов, РиÑто
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