Results 61 to 70 of about 6,170,041 (202)

SÍNTESE DE N-GLICOSILSULFONAMIDAS DERIVADAS DE D-GLICOSE E N-ACETILGLICOSAMINA

Química Nova, 2015
Herein, we report the synthesis of β-N-glycosylsulfonamides derivatives of D-glucose and N-acetylglucosamine using conventional methods. We also describe a procedure that allows the preparation of these compounds in good yields without the anomerization ...
Lucas L. Franco, Mário C. Brandão, José D. S. Filho, Ricardo J. Alves   +3 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Tagelda n Kuku d tqerrabin d lǧerrat tinmettiyin i d-teǧǧa

Revue d'Histoire Méditerranéenne
Deg umagrad-a, nemmeslay-d ɣef yiwet n tgelda i yesɛan azal meqqren deg umezruy atrar n Lezzayer s umata ladɣa amezruy n tmurt n Leqbayel, tagi d tageda n Kuku i d-ibanen deg useggas 1511, seld tuṭṭfa n temdint n Bgayet s ɣur Spenyul deg useggas 1510 ...
BENCHIKHE Ali
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

N,N-Dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine monohydrate

IUCrData, 2018
The asymmetric unit of the title compound, C7H9N5·H2O, consists of two formula units differing slightly in the orientation of the dimethylamino groups. In the crystal, a combination of O—H...N and N—H...O hydrogen bonds involving the water molecules of ...
Mohamed El Hafi, Mohammed Boulhaoua, Sanae Lahmidi, Youssef Ramli, El Mokhtar Essassi, Joel T. Mague   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Degree sequence for k-arc strongly connected multiple digraphs

Journal of Inequalities and Applications, 2017
Let D be a digraph on { v 1 , … , v n } $\{v_{1},\ldots, v_{n}\}$ . Then the sequence { ( d + ( v 1 ) , d − ( v 1 ) ) , … , ( d + ( v n ) , d − ( v n ) ) } $\{ (d^{+}(v_{1}), d^{-}(v_{1})), \ldots, (d^{+}(v_{n}), d^{-}(v_{n}))\}$ is called the degree ...
Yanmei Hong, Qinghai Liu
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Quantum-group-invariant D n + 1 2 $$ {D}_{n+1}^{(2)} $$ models: Bethe ansatz and finite-size spectrum

Journal of High Energy Physics
We consider the quantum integrable spin chain models associated with the Jimbo R-matrix based on the quantum affine algebra D n + 1 2 $$ {D}_{n+1}^{(2)} $$ , subject to quantum-group-invariant boundary conditions parameterized by two discrete variables p
Holger Frahm, Sascha Gehrmann, Rafael I. Nepomechie, Ana L. Retore   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source