Results 101 to 110 of about 6,056,925 (239)

Проценка на ризик за безбедноÑта на водата за пиење и водоÑнабдувањето во КичевÑкиот регион за периодот од 1996-2013 година

, 2017
Intensification of systemic chemotherapy with in- clusion of high doses methotrexate (MTX) has contributed to the improvement of event-free survival in children with acute lymphoblastic leukemia (ALL). Despite this benefit, this agent might cause serious
ЕфтимијадоÑка (Eftimijadoska), Фани (Fani)
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

СÑавниÑелÑнÑй анализ ÑпекÑÑов ÑоÑолÑминеÑÑенÑии ÑÑда оÑганиÑеÑÐºÐ¸Ñ Ñоединений

, 2017
Григорий Андреевич Верхоглядов
openalex   +1 more source

Ðрхивы иÑтории, архивы памÑти. Графика ÐоÑми ЭÑканделла

, 2019
The aim is of this research is to reconstruct the poetic and political discourse of plastic artist Noemí Escandell (1942-2019) by analyzing the formats, use of photographic archives and narrative thickness of her works created by the end of the sixties ...
Lucero, María Elena
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

ÐолÑÑение ÑÑабилÑной ÑоÑÐ¼Ñ Ð¿Ð»Ð°Ð·Ð¼Ð¸Ð´Ð½Ð¾Ð¹ ÐÐРиз ÑÑамма E. COLI DH10B/R

, 2017
Анатолий Анатольевич Ельцов
openalex   +1 more source

Вино превращаетÑÑ Ð² воду: ÑвÑщенные предметы и их выживание в музеÑÑ…

, 2019
This paper deals with the symbolic transformation among sacred objects when those became museology pieces. Removing those objects from the environment and functions which originally they are intended to be use, conferring them different meaning and uses,
Corrêa Frossard, Gabriela, de Oliveira Valinhas , Mannuella Luz   +1 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

ÐналÑз ÑÑнкÑÑÑ Ð½Ð¸Ñок Ñ ÑвоÑÐ¸Ñ Ð½Ð° ÑÑеÑеÑолÑÑÑаз, ÑÐºÐ¸Ñ Ð»ÑкÑвали за Ð´Ð¾Ð¿Ð¾Ð¼Ð¾Ð³Ð¾Ñ ÐµÐ½Ð´Ð¾ÑкопÑÑÐ½Ð¸Ñ Ð¼ÐµÑодÑв, залежно вÑд ÑеÑмÑнÑв пеÑебÑÐ²Ð°Ð½Ð½Ñ ÐºÐ¾Ð½ÐºÑеменÑÑв Ñ ÑеÑоводÑ

, 2015
Р. О. Білоруський, Ю. Б. Борис, В. В. Дмитріенко   +2 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source